Lnp obituaries

In Lancaster County, there were 2 newly reported COVID-19 cases and 0 newly reported COVID-19 deaths on Aug 31, 2021. 7 deaths per 100,000, while in the North. Civil Marriages at register offices, or non-conformist churches where a registrar was required to be present at the ceremony. Share Condolences ›. 1 around 10 a. Obituaries can be used to uncover information about other relatives or to confirm that you have the right person in Lancaster, Pennsylvania. William "Bill" Lloyd Strawn, 77, Lancaster, passed away Tuesday, August 17, 2021 at Mount Carmel East Hospital. Sep 10, 2021 · A woman found dead at her home in Lancaster County was sexually assaulted prior to being strangled, according to the Lancaster County District Attorney's office. Blevins, William Edward 93, formerly of Lancaster. An investigation was underway Saturday into the stabbing death of a man in Lancaster. By David Nowell. 27, on 200th Street East near East Avenue I, according to a news release from the Sheriff's Information Bureau. 16 hours ago · Betsy Lynn Lancaster Moran passed away 2021-09-09 in Bridgeport, West Virginia. When getting ready to write an obituary, there are several things you should keep in mind. 2 days ago · A 65-year-old woman found dead inside her Lancaster County home last week died of strangulation, the coroner has ruled, according to the LNP newspaper. Enquires to HD Tribe 01273 452169. Friday, Aug. 5, in the 44200 block of Beech. The young people in The Fault in Our Stars confront the issue of dying on a daily basis. Northern Lancaster County Regional Police Department reported a crash involving a pickup truck and tractor-trailer at the intersection of Main Street and Graystone Road in East Petersburg Borough. Deputies were sent to 200th Street East and East. There have been 13 total deaths reported so far in October, a 54 percent increase from the 24 at the start of the month. Someone described as a person of interest has been detained for questioning following the shooting deaths of two men in Lancaster Monday morning, authorities said. On Wednesday, the patient count stood at 85. Brown Stephen James Aged 65 years died suddenly on Friday 27th August 2021. Instance of. Lancaster County investigators said they now have answers, nearly 14 years after the murder of "Baby Mary Anne. Obituaries In Lancaster - Ohio. Search Obituaries. Celebrate and remember the lives we have lost in Lancaster, California. Death Notice. He was preceded in death by his wife, Dona L. Leave your condolences to the family on this memorial page or send flowers to show you care. If you don't see the obituary or death record that you are looking for, use this form to search our entire database. Authorities say they were called to a home at 202 West Strawberry Street to check on an. Full story. Obituaries. Bull - Apr 19, 2020. The incident was reported around 12:12 p. Nora Sanchez, 65, of the 300 block of East Main Street in New Holland was found dead in her home on Sept. There are 879 cases of coronavirus confirmed in Lancaster , United Kingdom, as of Wednesday, 8th of September 2021. 59 at Chevron at 2301 W Lancaster Blvd, which GasBuddy clocked as the most. 1 around 10 a. The coroner determined the manner of death. The Health Department reports that over the weekend, there were 174 cases confirmed Saturday and 64 on Sunday. LANCASTER - A man shot to death in Lancaster Sunday night has been identified. Sadly, we had to say goodbye to Wanda Romero (57 Years old). The coroner …. Died on Wednesday, the 13th ult. Holden, 46 - Feb 19, 2019. This is the full obituary story where you can express condolences and share memories. Sunday in the 44200 block of Beech Avenue, according to Deputy. February 19, 1940 - July 27, 2021. The shooting was reported at 10:28 p. The Lincoln-Lancaster Health Department reported Thursday that three more people have died of COVID-19. Dorothy Shull. Note: Not all entries have the age at death indexed. 2 days ago · A 65-year-old woman found dead inside her Lancaster County home last week died of strangulation, the coroner has ruled, according to the LNP newspaper. , on September 14, 2020. Leon Gilmore charged with murder following brother's death in Lancaster. Leave your condolences to the family on this memorial page or send flowers to show you care. Snyder Funeral Home & Crematory, 717-393-9661 Read. LANCASTER, Pa. He was born February 15, 1957 in Atlanta, Georgia, the son of the late Mr. Susan Lewis. Donald Meshey Jr. Lancaster County, Pennsylvania Obituary and Death Notices Collection. Bill graduated from Lancaster High School in 1962, was a US Army Veteran, worked 35 years for Western Electric, AT&T. All deeds also require a Form 521 - Real Estate Transfer Statement. Yet, for those who have experienced the death of a family member or friend, an obituary means so much more. Obituaries. Those two municipalities account for 72% of the deaths in the county. Melvin Boulware. In that time they have reported 29. Browse Obituaries and Death Records in Lancaster, New York. Man Found Shot to Death in Lancaster. We want you to know that we appreciate your attention-to-detail at this most difficult time. Eagle Gazette : Obituaries in Lancaster, Ohio (OH) - Find online obituaries in Eagle Gazette. Lancaster, 75 of Gaithersburg, MD passed away on Thursday, September 9, 2021 at CaroMont Regional Hospital. 14 through 22, according to data from the county’s coroner, Dr. William "Bill" Lloyd Strawn, 77, Lancaster, passed away Tuesday, August 17, 2021 at Mount Carmel East Hospital. Deputies were sent to 200th Street East and East Avenue I about 12:10 p. The surging market is fueling a whole host of problems - including pushing more people into homelessness. We are constantly trying to improve our data and make the search for obituaries as easy as possible. Esri publishes a set of ready-to-use maps and apps that are available as part of ArcGIS. LINCOLN, Neb. , according to the Los Angeles County Sheriff's Department. Wittenauer, 69 - Jun 14, 2019. Celebrate and remember the lives we have lost in Lancaster, California. COVID-19 hospitalizations and deaths have continued to rise in Lancaster County, even as the pace of new cases is showing some signs of leveling off after weeks of increases. LANCASTER COUNTY S. She was a Special Education teacher at South Middle School. He was married to Shelia Stradford. LINCOLN, Neb. Browse Obituaries and Death Records in Lancaster, Illinois Paul E. Celebrate and remember the lives we have lost in Lancaster, California. Pennsylvania Death Certificates, 1906-1968 (indexed) (at Ancestry/requires payment); includes scanned copies of the death certificates Pennsylvania Death Records Indexes, 1906-1970 (index only; free) PDF files; you must search each year separately; for some years surnames are listed by Soundex code; from the Pennsylvania. August 24, 2021 (46 years old) View obituary. He was a son of the late Roosevelt "Bud" Gaither and the late Alfreda Dean Gaither. Due to social distancing rules we have limited space for people attending the Coroner's Court in all venues. The News-Journal. The deaths brought the county's total to 13 — with Ferrer saying the death of a 17-year-old boy in Lancaster that was reported Tuesday is no longer considered a coronavirus case, pending a. on reports of a possible body dumped on the side of the street, according to the Los Angeles County. Susan Lewis. Hospitalizations for COVID-19 positive patients: 20 with 14 from Lancaster County (none on ventilators) and six from other communities (one on a ventilator). See reviews, photos, directions, phone numbers and more for the best Funeral Directors in Lancaster, SC. One of our professional funeral arrangers will call you shortly, or you may choose to call us now at (717) 394-5300. According to the. 68509-5065. 87, husband of Josephine C. , as Daily Voice…. From Wikimedia Commons, the free media repository. A Lancaster County man wanted for murder in the shooting death of a man Aug. The deceased was a man in his 80s. 7) - first identified in the U. September 09, 2021. Obituaries In Lancaster - Ohio. Special testing at the Nebraska Public Health Lab identified the delta variant (B. Celebrate and remember the lives we have lost in Lancaster, Pennsylvania. She was born on March 4. The shooting was reported at 1:52 a. The Health Department reports that over the weekend, there were 174 cases confirmed Saturday and 64 on Sunday. September 09, 2021. Deaths in Lancaster on YP. The deaths brought the county's total to 13 — with Ferrer saying the death of a 17-year-old boy in Lancaster that was reported Tuesday is no longer considered a coronavirus case, pending a. July 30, 2021 (77 years old) View obituary. Find an obituary, get service details, leave condolence messages or send flowers or gifts in …. Stephen Diamantoni. The death can then be registered with the Registrar of Births Marriages and Deaths and the funeral can then take place. Inaccuracies and exaggerations were always common, so take the information detailed in them with a pinch of salt. August 10, 2021 at 11:59 am EDT By WSOCTV. Death Records are kept by …. (KLKN) – Another day with three COVID deaths in Lancaster County and a total of 102 positive cases. Nora Sanchez, 65, of the 300 block of East Main Street in New Holland was found dead in her home on Sept. The Plaindealer. She was fully vaccinated, but according to Scott Holmes with the. Stephen Diamantoni. Lancaster County has continued to see increases in new COVID-19 cases and hospitalizations over the past week, and deaths, too, are now showing some signs of an …. 9, 1951, in …. 5, in the 44200 block of Beech. Betsy Lynn Lancaster Moran passed away 2021-09-09 in Bridgeport, West Virginia. William Gerald Friedt. The coroner determined the manner of death. There were 96 new cases confirmed Monday. August 22, 2021. Holden, 46 - Feb 19, 2019. August 28, 2021 (88 years old) View obituary. This page shows only the 20 most recent obituaries in Lancaster, South Carolina. Authorities say they were called to a home at 202 West Strawberry Street to check on an. If you don't see the obituary or death record that you are looking for, use this form to. Friday, Aug. The Lancaster Examiner. The Lincoln-Lancaster County Health Department also reported fourteen new cases today, and 32 people in. Dorothy Shull. 3, 2020 at 1:50 PM PST. Apr 12, 2021 · 1 COVID-19 Death Sunday in Lancaster County. A registrar cannot register the death or issue a death certificate until the body is released by the coroner. Arthur Robert Benson, 77 - Jan 17, 2020. Lancaster City Council President Ismail Smith-Wade El speaks at a press conference following the shooting and protests in Lancaster, Pa. us Prepayment of all requests is required and records can be emailed directly to you. Gary Anthone discusses the current treatments for coronavirus. This brings the total number of deaths in Lancashire hospitals to 14, with six at Royal Lancaster Infirmary, three in hospitals managed by the Lancashire Teaching Hospitals NHS Trust, two in hospitals managed by the East Lancashire Hospitals Trust and three at Blackpool Victoria Hospital. This brings the number of deaths to 259. Services by AMOS-CARVELLI FUNERAL HOME. New Deaths Per Day. Recognized among a selective 5% of attorneys. Nora Sanchez, 65, of the 300 block of East Main Street in New Holland was found dead in her home on Sept. For the purposes of registering Births and Deaths, Lancashire was divided into a number of Registrars' Sub-Districts, which could cover anything from part of a large town, up to a group of several dozen rural parishes. Add a photo free. Jacqueline Loraine Field. 04/12/1945 - 08/26/2021. Deaths reported Monday were a man in his 40s, a woman in her 50s and a woman. A woman found dead at her home in Lancaster County was sexually assaulted prior to being strangled, according to the Lancaster County District Attorney's office. He was 34-year-old DeJuan Beverly of Palmdale, according to the Los Angeles County Coroner's Office. Man, 34, Shot To Death In Lancaster, Shooter Still. The shooting was reported around 10:25 p. A woman in her 80’s who was in the hospital and unvaccinated passed away. Find an obituary, get service details, leave condolence messages or send flowers or gifts in …. Southern Lancaster County Deaths 1894 - 1907 Southern Lancaster County Historical Society. Application for Amendment With Instructions : If adding the father to the birth certificate, please contact this office for instructions and the proper form. , on September 14, 2020. COVID-19 hospitalizations and deaths have continued to rise in Lancaster County, even as the pace of new cases is showing some signs of leveling off after weeks of increases. Three men died according to the latest report from the Lincoln-Lancaster County. On Saturday the cheapest gallon of unleaded regular in the area was at Costco at 1141 W Ave L. 1 around 10 a. Nora Sanchez, 65, of the 300 block of East Main Street in New Holland was found dead in her home on Sept. If you don't see the obituary or death record that you are looking for, use this form to search our entire database. 99 per gallon Wednesday, compared to $4. These can include Lancaster County death certificates, local and Pennsylvania State death registries, and the National Death Index. It is a bittersweet reminder of all we've lost, but it can also help us to remember all we enjoyed while they were alive. 1, according to the Los Angeles County Sheriff's Department. Lancaster, SC. The Health Department reports that over the weekend, there were 174 cases confirmed Saturday and 64 on Sunday. Two elderly patients at Royal Lancaster Infirmary have sadly passed away due to Coronavirus. In these cases, the certificate may or may not be the one you seek. Sunday, Sept. Holden, 46 - Feb 19, 2019. , as Daily Voice…. He was the loving husband of Shirley (LeFevre) Gochenauer for 70 years. August 10, 2021 at 11:59 am EDT By WSOCTV. The following deaths are reportable to the Coroner in Lancaster County: Any death in which trauma, falls or fractures, chemical injury, asphyxia, exposure, fire, drug overdose, or reaction to drugs or medical treatment was a primary, secondary, direct or indirect, contributory, aggravating, or precipitating cause of death. 13/11/2019. Stephen Diamantoni. There are two more COVID-19 deaths in Lancaster County, a man in his 40’s and a man in his 60’s, both were hospitalized and unvaccinated. He was a long-time member of the Willow Street read more …. DaLauro - Apr 18, 2020. Kulp February 22, 1936 - June 8, 2004 Clyde S. Add a photo free. Her death brings the county’s total to 240 since the pandemic began. Wittman - Apr 2020. Bollinger Funeral Home, 304-343-4200 Read more. According to the. Gerane Nelson - May 12, 2018. Recognized among a selective 5% of attorneys. Jeanne Teresa Grady - Dec 24, 2018. Nebraska Vital Records. Dizon, 81, of Lancaster, passed away on Friday, August 27, 2021 at Lancaster General Hospital. This page shows only the 20 most recent obituaries in Lancaster, New Hampshire. Lancaster, PA 17603. Sep 10, 2021 · A woman found dead at her home in Lancaster County was sexually assaulted prior to being strangled, according to the Lancaster County District Attorney's office. The pandemic’s toll here now stands at 1,076, including at least two so far in the opening days of September. By Sunday night, Ricardo's death was seen by some as yet another example of the need for police reform. If you don't see the obituary or death record that you are looking for, use this form to. Sep 08, 2021 · A 65-year-old New Holland woman found dead inside her home last week died of strangulation, according to Lancaster County Coroner Dr. Enquires to HD Tribe 01273 452169. Echovita is an archive of public obituaries and death notices to keep you informed about people who have passed away in your city. The following listing shows which marriage records are held by the Lancashire register offices, and the years covered so far by the indexes on this web-site. Upon his death his titles and estates were forfeited, but in 1323 his younger brother Henry successfully petitioned to take possession of the Earldom of Leicester, and in 1326 or 1327 Parliament posthumously reversed Thomas's conviction, and Henry was further permitted to take possession of the Earldoms of Lancaster, Derby, Salisbury and Lincoln. If you don't see the obituary or death record. Lancaster County investigators said they now have answers, nearly 14 years after the murder of "Baby Mary Anne. This is the full obituary story where you can express condolences and share memories. The legend is directly above the maps. Find an obituary, get service details, leave …. John Oliver "Jo" DFC, CEng, FRAeS, died on 10th August 2019 aged 100, after a short illness. Application for Amendment With Instructions : If adding the father to the birth certificate, please contact this office for instructions and the proper form. LANCASTER (CBSLA) - An investigation is underway into the deaths of two people in Lancaster Friday morning. 1547 Obituaries. The shooting was reported at 10:28 p. Death Notice. Friday, Aug. Biddle - Nov 19, 2018. This brings the number of deaths to 259. It is a bittersweet reminder of all we've lost, but it can also help us to remember all we enjoyed while they were alive. com A 65-year-old woman found dead inside her Lancaster County home last week died of strangulation, the coroner has ruled, according to the LNP newspaper. Three men died according to the latest report from the Lincoln-Lancaster County. To submit an obituary to Lancaster Eagle-Gazette, send an email to [email protected] It includes the following information: name of deceased, age, marital status, place of birth, occupation, date of death, place of death, cause of death, duration of last illness, and the place and date of interment. Several weeks of increases recently pushed COVID-19 case rates and hospitalizations back to their springtime levels in Lancaster County, and now deaths, too, have …. She was the wife of Fred W. He was born Feb. Antelope Valley Hospital in Lancaster, Calif. Leave your condolences to the family on this memorial page or send flowers to show you care. 7 deaths per 100,000, while in the North. The deaths were a man in his 60s who was hospitalized and vaccinated, a man in his 80s who. News Sports HS Sports Life & Events Obituaries E-Edition Legals. 50 North Queen St. Today, it was a woman in her 80’s who was in a hospital at the time she passed away. Baptismal records, 1730-1786 and marriage records, 1735-1821 of the Moravian Church in Lancaster, Pennsylvania Family History Library. and Georgianna Dow. Frick was born Nancy Jane Johnston on June 8, 1927 in Columbus, Ohio. Receive obituaries. She was born on March 4. Lancaster City Council President Ismail Smith-Wade El speaks at a press conference following the shooting and protests in Lancaster, Pa. Family members filed a lawsuit Wednesday seeking $10. LANCASTER - Dennis Arthur Belcher, 70, of Lancaster, widower of Dinah K. The Lancaster Examiner. Category:Deaths in Lancaster, Pennsylvania. The incident was reported around 12:12 p. Dorothy Shull. , according to the Los Angeles County Sheriff's Department. Three more residents have died from COVID-19, bringing the total number of deaths in Lancaster County to 70, the Lincoln. Donations in his memory, if desired, to the RAF Benevolent Fund or IBCC. Stephen Diamantoni. Donald Meshey Jr. Receive obituaries. Timothy "Tim Tim" Asantee McCain, 21, was served. Through our advanced obituary search, you may search our database of obituaries by name, location, date of death and keywords. (KABC) -- The boyfriend of the mother of a 10-year-old Lancaster boy who died in his home last week has been arrested on suspicion of murder, authorities said. and Georgianna Dow. Inquest hearings. For the purposes of registering Births and Deaths, Lancashire was divided into a number of Registrars' Sub-Districts, which could cover anything from part of a large town, up to a group of several dozen rural parishes. The Age and Lancaster and Chester County Weekly Gazette. A 34-year-old man was fatally shot Sunday in Lancaster. LANCASTER - A 34-year-old man was fatally shot Sunday in Lancaster. August 12, 2021 (67 years old) View obituary. Lancaster County Lancaster DA: Police investigating death of New Holland woman as homicide The body of Nora Sanchez, 65, was found in her home on Sept. COVID-19 hospitalizations and deaths have continued to rise in Lancaster County, even as the pace of new cases is showing some signs of leveling off after weeks of increases. In southcentral Pennsylvania, York County recorded its second death and Lancaster County added three deaths for a total of 14. Lancaster family accuses LA County of failing to prevent woman's death. The mystery of who murdered fourteen year old Sarah Boehm remains unsolved more than twenty years after her disappearance in 1994. Donald Meshey Jr. The News-Journal. Lancaster police say a man was arrested after he killed his father and dismembered his body. , 60, of Lancaster, passed away Wednesday, August 25, 2021. Services by Coastal Cremation Services. It is a bittersweet reminder of all we've lost, but it can also help us to remember all we enjoyed while they were alive. 20 hours ago · Lancaster County Lancaster DA: Police investigating death of New Holland woman as homicide The body of Nora Sanchez, 65, was found in her home on Sept. Mennonite Home Communities reported the death of two. Born in Willow Street, PA, he was the son of the late Harry F. LANCASTER - A man fatally shot in Lancaster last week has been identified. One of our professional funeral arrangers will call you shortly, or you may choose to call us now at (717) 394-5300. Mathias Ault, in the 105th year of his age. The Age and Lancaster and Chester County Weekly Gazette. Both the man in his 30s and man in his 60s were. Leave your condolences, photos and videos on her commemorative page and pay homage to her or send flowers to show you care. Services by Bowers Funeral Home. Ancestry ($) 1852-1855 Death Registrations, 1852-1855 at Lancaster County Archives. to the scene, where they found the unidentified victim with gunshot wounds to his upper body, said Deputy Miguel Meza of the Sheriff's Department's Information Bureau. 29, 2021, at MUSC-Lancaster. Co-op Funeralcare, Lancaster. John Oliver "Jo" DFC, CEng, FRAeS, died on 10th August 2019 aged 100, after a short illness. Phone (717)299-8381. It includes the following information: name of deceased, age, marital status, place of birth, occupation, date of death, place of death, cause of death, duration of last illness, and the place and date of interment. He was preceded in death by his wife, Dona L. Snyder Funeral Home & Crematory, 717-393-9661 Read. This page shows only the 20 most recent obituaries in Lancaster, Minnesota. Deaths Reported for Sep 03, 2021. Dale Lancaster passed away 2021-07-17 in Scarborough, Maine. Total number of deaths: 239. Find the obituary of Karaar Kendricks (1979 - 2021) from Lancaster, CA. 1 around 10 a. Garcia, 60. Search Lancaster County property tax and assessment records by owner name, property address or property id number. See reviews, photos, directions, phone numbers and more for the best Funeral Directors in Lancaster, VA. He was 41-year-old Bryan Roy Anderson of Quartz Hill, according to Sarah Ardalani of …. The News-Journal. By News Apr 12, 2021 | 4:40 AM. Bull - Apr 19, 2020. Click here to read more Willie Jackson, 68. Antelope Valley Hospital in Lancaster, Calif. If you have not been called to a hearing but are intending to attend to observe please advise the coroner's service immediately on 01772 536536. The Plaindealer. Martin, age 82 of Lancaster, passed away at her home on Sunday, September 5, 2021. After recording just six deaths in all of July, the county recently had five deaths over nine days, from Aug. LANCASTER - A 34-year-old man was fatally shot Sunday in Lancaster. The Lancaster Examiner. Carol Lynn Senig 73, of Lancaster, Ohio passed away unexpectedly Friday July 23, 2021. George Jacob Martz, 1869-1878 : comprising deaths, marriages, and baptisms during his ministerium at Womelsdorf Lutheran Church, Berks County, and Lutheran churches of the. August 30, 2021 (92 years old) View obituary. See reviews, photos, directions, phone numbers and more for the best Funeral Directors in Lancaster, SC. Browse Lancaster Guardian obituaries, conduct other obituary searches, offer condolences/tributes, send flowers or create an online memorial. Stephen Diamantoni. It includes the following information: name of deceased, age, marital status, place of birth, occupation, date of death, place of death, cause of death, duration of last illness, and the place and date of interment. Sunday, Sept. Over the weekend three more deaths were registered by the Trust, including a 72-year-old man, a 79-year-old woman and a woman in her 80s. Lancaster obituaries, on the other hand, are dictated entirely by the family. Through our advanced obituary search, you may search our database of obituaries by name, location, date of death and keywords. Graveside Friday at View full obituary. The Lancaster Examiner. Over the past two weeks, the county has averaged about one death per day, a pace similar to March, April and. August 25, 2021 (84 years old) View obituary. If you don't see the obituary or death record that you are looking for, use this form to search our entire database. Explore Life Stories, Offer Condolences & Send Flowers. A fairly recent phenomenon is the archiving of these Lancaster obituaries, first through microfilm, and then through online databases. Lancaster added 15 new confirmed COVID-19 cases since Saturday, bringing the total to 771 cases. The Lancaster Eagle-Gazette is the number one source for Lancaster, Fairfield County and Ohio breaking news, sports, photos and videos. The Lancaster County Coroner's Office later confirmed that the head from the freezer was a human head. The coroner determined the manner of death. Read Notice ›. If an inquest is needed, a death cannot be registered until the inquest has been completed. 08/14/1947 - 07/23/2021. An assisted living home in Lancaster has reported six of its residents have died over the last two days apparently due to the coronavirus. Man Found Shot to Death in Lancaster. City Council unanimously passed final reading Tuesday, June 26, of its $21. Send us an email with your request: [email protected] LINCOLN, Neb. The Lincoln-Lancaster County Health Department is showing one more COVID death in the Friday report. Brown Stephen James Aged 65 years died suddenly on Friday 27th August 2021. Johnson Marvin Lancaster and the late Mrs. Lancaster worked for Master Manufacturing for 17 years as a Heat Treatment Operator. Lancaster Guardian notices and Death Notices for Lancaster Lancashire area. Seven deaths is a new single-day high for the Lancaster County area. The pandemic’s toll here now stands at 1,076, including at least two so far in the opening days of September. A fairly recent phenomenon is the archiving of these Lancaster obituaries, first through microfilm, and then through online databases. county of Pennsylvania. The Plaindealer. Lancaster County investigators said they now have answers, nearly 14 years after the murder of "Baby Mary Anne. Quartz Hill has 10 deaths, with two in Lake Los Angeles and Acton and a single death each in Del Sur and Desert View Highlands. HOUSE OF LANCASTER The name House of Lancaster is commonly used to designate the line of English kings immediately descended from John of Gaunt, the fourth son of Edward III. Search Lancaster obituaries and condolences, hosted by Echovita. Frizzell , 38 - Apr 19, 2020. Graveside Friday at View full obituary. The Lancaster Eagle-Gazette is the number one source for Lancaster, Fairfield County and Ohio breaking news, sports, photos and videos. He was born Feb. Sep 10, 2021 · A woman found dead at her home in Lancaster County was sexually assaulted prior to being strangled, according to the Lancaster County District Attorney's office. Shawn David Merritt, 33, passed away Tuesday, June 26, 2012. Sunday, Aug. Jeanne Teresa Grady - Dec 24, 2018. This is the full obituary story where you can express condolences and share memories. The Age and Lancaster and Chester County Weekly Gazette. Carol Lynn Senig 73, of Lancaster, Ohio passed away unexpectedly Friday July 23, 2021. There were 96 new cases confirmed Monday. The death toll in Lancaster County is now 58. Most older obituaries will include some pieces of family information. He attended North High School. The Health Department reports that over the weekend, there were 174 cases confirmed Saturday and 64 on Sunday. Lancaster County has continued to see increases in new COVID-19 cases and hospitalizations over the past week, and deaths, too, are now showing some signs of an …. 1, and an autopsy determined she died of. (LANCASTER, CA) According to Lancaster gas price data, you could be saving up to $0. 29, 2021, at MUSC-Lancaster. New Deaths Per Day. Baptismal records, 1730-1786 and marriage records, 1735-1821 of the Moravian Church in Lancaster, Pennsylvania Family History Library. Sep 08, 2021 · A 65-year-old New Holland woman found dead inside her home last week died of strangulation, according to Lancaster County Coroner Dr. Shawn David Merritt, 33, passed away Tuesday, June 26, 2012. 7 deaths per 100,000, while in the North. Nowosiadly - Apr 2020. Tim Callahan Obituary – Death – Tim Callahan of Lancaster, Kansas, has passed away unexpectedly. A fairly recent phenomenon is the archiving of these Lancaster obituaries, first through microfilm, and then through online databases. The situation began at 7:36 a. Bill graduated from Lancaster High School in 1962, was a US Army Veteran, worked 35 years for Western Electric, AT&T. Belcher, passed away Sunday, Aug. All deeds also require a Form 521 - Real Estate Transfer Statement. Total number of COVID-19 variant cases in Lancaster County: 254 Alpha (B. Several weeks of increases recently pushed COVID-19 case rates and hospitalizations back to their springtime levels in Lancaster County, and now deaths, too, have …. (KABC) -- The boyfriend of the mother of a 10-year-old Lancaster boy who died in his home last week has been arrested on suspicion of murder, authorities said. (Kate Landis/WITF) Calls for change. Deputies assigned to the. There have been at least 12 deaths since Aug. The shooting was reported around 10:25 p. LANCASTER COUNTY S. Four Deaths In Lancaster Outbreak. The coroner determined the manner of death. , as Daily Voice…. He was 41-year-old Bryan Roy Anderson of Quartz Hill, according to Sarah Ardalani of the Los Angeles County Coroner’s Office. A registrar cannot register the death or issue a death certificate until the body is released by the coroner. Ault came to America in 1752, a servant to General Deshee. (KLKN) - Officials with the Lincoln-Lancaster County Health Department (LLCHD) report two new COVID deaths in the community, with the total now at 152. Ballard, 83 - May 5, 2019. Ian John ATKINSON. The Semi-Weekly New Era. The News-Journal. Deaths Reported for Sep 03, 2021. Carole Doherty. Lancashire Births Marriages & Deaths Indexes. Lancaster's age-standardised mortality rate was 24 deaths involving Covid-19 per 100,000. Note: Not all entries have the age at death indexed. Esri publishes a set of ready-to-use maps and apps that are available as part of ArcGIS. Lancaster obituaries, on the other hand, are dictated entirely by the family. 99 per gallon Wednesday, compared to $4. Obituaries In Lancaster - Pennsylvania. Donald Meshey Jr. Browse Obituaries and Death Records in Lancaster, Ohio Angie Richards Faddis , 42 - Apr 23, 2020 Jason R. The 1893-1907 Lancaster County Death Registration is valuable since it records deaths before Pennsylvania began keeping them in 1906. , over the weekend. Browse Obituaries and Death Records in Lancaster, Kansas Judy Ann Brown , 67 - Dec 1, 2019 Robert Charles Dorssom , 78 - Nov 16, 2019. Case numbers continue to climb. Celebrate and remember the lives we have lost in Lancaster, California. Lancaster Guardian Notices. The deaths brought the county's total to 13 — with Ferrer saying the death of a 17-year-old boy in Lancaster that was reported Tuesday is no longer considered a coronavirus case, pending a. View recent online obituaries and memorial websites for people from Lancaster, Pennsylvania. There are two more COVID-19 deaths in Lancaster County, a man in his 40’s and a man in his 60’s, both were hospitalized and unvaccinated. The News-Journal. The flu contributed to another seven deaths in the past week of a flu season that shows no signs of letting up, according to data the state Department of Health released Tuesday. 1, and an autopsy determined she died of. From cities to rural towns, stay informed on where COVID-19 is spreading to understand how it could affect families, commerce, and travel. First death due to Delta COVID-19 variant in Lancaster County. Use these powerful cause of death maps to compare the top 15 causes of death in Pennsylvania down to the county level. For the purposes of registering Births and Deaths, Lancashire was divided into a number of Registrars' Sub-Districts, which could cover anything from part of a large town, up to a group of several dozen rural parishes. This is the first reported death related to the delta variant in Lancaster County. The 20-year-old woman's name was Maura. It is a bittersweet reminder of all we've lost, but it can also help us to remember all we enjoyed while they were alive. 2 days ago · A 65-year-old woman found dead inside her Lancaster County home last week died of strangulation, the coroner has ruled, according to the LNP newspaper. Blevins, William Edward 93, formerly of Lancaster. Co-op Funeralcare, Lancaster. Nowosiadly - Apr 2020. The private records of Rev. Bill graduated from Lancaster High School in 1962, was a US Army Veteran, worked 35 years for Western Electric, AT&T. This page shows only the 20 most recent obituaries in Lancaster, Massachusetts. This brings the total number of deaths in Lancashire hospitals to 14, with six at Royal Lancaster Infirmary, three in hospitals managed by the Lancashire Teaching Hospitals NHS Trust, two in hospitals managed by the East Lancashire Hospitals Trust and three at Blackpool Victoria Hospital. 59 at Chevron at 2301 W Lancaster Blvd, which GasBuddy clocked as the most. LANCASTER - A man shot to death in Lancaster Sunday night has been identified. Deaths in Lancaster on YP. The coroner …. 684 likes · 1 talking about this. According to the. Select a city or town in California from the alphabetized list below. The Inquirer. 201 likes · 6 talking about this. Find an obituary, get service details, leave …. Evelio Villatoro Castillo. Deaths in Lancaster on YP. He was a long-time member of the Willow Street read more …. The deaths were a man in his 60s who was hospitalized and vaccinated, a man in his 80s who. This page shows only the 20 most recent obituaries in Lancaster, California. This brings the number of deaths to 259. Deaths reported Monday were a man in his 40s, a woman in her 50s and a woman. Sep 10, 2021 · A woman found dead at her home in Lancaster County was sexually assaulted prior to being strangled, according to the Lancaster County District Attorney's office. To submit an obituary to Lancaster Eagle-Gazette, send an email to [email protected] Proceeded in death by husband George Foor, husband William Rutherford, daughter Judith (Ervin)McGregor, Parents Alta R. Lancaster, PA obituary and death notices. The incident was reported around 12:12 p. com News Staff LANCASTER. Deaths and marriages, abstracted from newspapers, 1800-1906 Family History Library. Celebrate and remember the lives we have lost in Lancaster, California. (KLKN) – Another day with three COVID deaths in Lancaster County and a total of 102 positive cases. The Lancaster County Coroner's Office later confirmed that the head from the freezer was a human head. Call Us (803) 286-5000. Celebrate and remember the lives we have lost in Lancaster, Pennsylvania. The Morning Journal. Awarded to less than 1% of U. Search Obituaries. He was 41-year-old Bryan Roy Anderson of Quartz Hill, according to Sarah Ardalani of the Los Angeles County Coroner’s Office. Stock - Apr 19, 2020. Echovita is an archive of public obituaries and death notices to keep you informed about people who have passed away in your city. Demonstrators gathered to protest the death of 27-year-old man who was shot and killed by a police officer in Lancaster, Pa. LANCASTER - John Eric "Lawnmoe" Gaither, 57, died Tuesday, Aug. A 34-year-old man was fatally shot Sunday in Lancaster. This brings the number of deaths to 259. Death Notice. Southern Lancaster County Deaths 1894 - 1907 Southern Lancaster County Historical Society. It is with deep sorrow that we announce the death of Timothy Ziegler (64 Years old). Georgelis Injury Law Firm, P. 1, and an autopsy determined she died of. He was 41-year-old Bryan Roy Anderson of Quartz Hill, according to Sarah Ardalani of the Los Angeles County Coroner's Office. A courtyard area at the rear of the building provides a pleasant area for photographs with steps, pillars and a shrubbery background. Nora Sanchez, 65, of the 300 block of East Main Street in New Holland was found dead in her home on Sept. Parley Burk Sistar, 89 - Mar 22, 2020. Dearly beloved son of Cyril Brown (deceased) and Margaret Brown (deceased) beloved brother to. She was also the second teacher to pass away from COVID-19 in the Lancaster County School District this week. Sunday in the 44200 block of Beech Avenue, according to Deputy Tracy Koerner of the Los Angeles County Sheriff’s Department. The deceased has been. We also offer funeral pre-planning and carry a wide selection of caskets, vaults, urns and burial containers. Echovita is an archive of public obituaries and death notices to keep you informed about people who have passed away in your city. Authorities say they were called to a home at 202 West Strawberry Street to check on an. Family members filed a lawsuit Wednesday seeking $10. COVID-19 hospitalizations and deaths have continued to rise in Lancaster County, even as the pace of new cases is showing some signs of leveling off after weeks of …. The new figures, released by the five NHS trusts in the county, reveal that the new total for Lancashire is 714. LANCASTER - John Eric "Lawnmoe" Gaither, 57, died Tuesday, Aug. 5, in the 44200 block of Beech. The ground floor ceremony room has disabled access and seats 46 guests. Your efforts will help us better care for you, and your loved one. Named after. Find an obituary, get service details, leave condolence messages or send …. These can include Lancaster County death certificates, local and Pennsylvania State death registries, and the National Death Index. Find the obituary of Karaar Kendricks (1979 - 2021) from Lancaster, CA. Bill was born July 13, 1944 in Lancaster, Ohio, the son of the late Glenn Oscar Strawn and Mildred Gaye Dillon. A Lancaster High School student is the youngest person to die of the novel coronavirus in Dallas County, officials said Tuesday. September 09, 2021. Stephen Diamantoni. Obituaries In Lancaster - Ohio. 3, 2020 at 1:50 PM PST. Friday to the 1100 block of Ovington Street, where they found the victim, a. Eleanor Mends. Man Found Shot to Death in Lancaster. DaLauro - Apr 18, 2020. A daughter of the late Frank and Delphine Brevard Lucille Dease Campbell, 88. Follow new cases found each day and the number of cases and deaths in. 20 hours ago · Lancaster County Lancaster DA: Police investigating death of New Holland woman as homicide The body of Nora Sanchez, 65, was found in her home on Sept. Mathias Ault, in the 105th year of his age. 13/11/2019. Deaths in Lancaster on YP. The 20-year-old woman's name was Maura. Inaccuracies and exaggerations were always common, so take the information detailed in them with a pinch of salt. Mary Marcelette Fowler Lancaster - Mary Marcelette Fowler, 93, of Lancaster, Ohio, died peacefully on August 23, 2021 at the Smith's Mill Health Center, New Albany, Ohio. lawyers who have won million and multi-million dollar verdicts. Bishop Iola Bell Cunningham, 94, died Wednesday, June 20, 2012. Lancaster police say a man was arrested after he killed his father and dismembered his body. Confirmed cases of Covid-19 by borough as of May 8: The coronavirus death toll in Lancashire has risen by four in the latest NHS England figures. A registrar cannot register the death or issue a death certificate until the body is released by the coroner. The young people in The Fault in Our Stars confront the issue of dying on a daily basis. Browse the most recent Lancaster, Pennsylvania obituaries and condolences. Find the obituary of Wanda Romero (1964 - 2021) from Lancaster, PA. The Lincoln-Lancaster County Health Department reported one death and 183 new cases of COVID-19 in their area today. Man Found Shot to Death in Lancaster. This page shows only the 20 most recent obituaries in Lancaster, South Carolina. Like our page to stay informed about passing of a loved one in Lancaster, California on facebook. When getting ready to write an obituary, there are several things you should keep in mind. Donald Meshey Jr. Box 95065, Lincoln, Nebraska. Inaccuracies and exaggerations were always common, so take the information detailed in them with a pinch of salt. Celebrate and remember the lives we have lost in Lancaster, Pennsylvania. The Groffs Family Funeral & Cremation Services Inc. James Henry Walck - Apr 19, 2020. Application for Amendment With Instructions : If adding the father to the birth certificate, please contact this office for instructions and the proper form. LANCASTER, S. Read Notice ›. 2 days ago · A 65-year-old woman found dead inside her Lancaster County home last week died of strangulation, the coroner has ruled, according to the LNP newspaper. , 60, of Lancaster, passed away Wednesday, August 25, 2021. With heavy hearts, we announce the death of Karaar Kendricks (42 Years old). Stock - Apr 19, 2020. See reviews, photos, directions, phone numbers and more for the best Funeral Directors in Lancaster, OH. She was fully vaccinated, but according to Scott Holmes with the. Ian John ATKINSON. Upon his death his titles and estates were forfeited, but in 1323 his younger brother Henry successfully petitioned to take possession of the Earldom of Leicester, and in 1326 or 1327 Parliament posthumously reversed Thomas's conviction, and Henry was further permitted to take possession of the Earldoms of Lancaster, Derby, Salisbury and Lincoln. The figures come just a few months after police officer Benjamin Monk was. Bollinger Funeral Home, 304-343-4200 Read more. 684 likes · 1 talking about this. LANCASTER - A man shot to death in Lancaster Sunday night has been identified. LANCASTER (CNS) - A man in his 30s was found today in the dirt on the side of a street in Lancaster dead from gunshot wounds. He was 41-year-old Bryan Roy Anderson of Quartz Hill, according to Sarah Ardalani of the Los Angeles County Coroner's Office. John Valerio. Obituaries In Lancaster - Pennsylvania. Garcia, 60. From cities to rural towns, stay informed on where COVID-19 is spreading to understand how it could affect families, commerce, and travel.


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Summary of the Public Assessment Report

Authorisation for Temporary Supply, COVID-19 mRNA Vaccine BNT162b2 (BNT162b2 RNA) concentrate for solution for injection

Department of Health and Social Care (DHSC), Pfizer Limited & BioNTech Manufacturing, GmbH

Lay summary, COVID-19 mRNA Vaccine BNT162b2 concentrate for solution for injection (BNT162b2 RNA)

This is a summary of the Public Assessment Report (PAR) for COVID-19 mRNA Vaccine BNT162b2. It explains how this product was assessed and authorised under Regulation 174 of the Human Medicine Regulations, as well as its conditions of use. It is not intended to provide practical advice on how to use this product.

The product will be referred to as BNT162b2 in this lay summary for ease of reading.

For practical information about using BNT162b2 patients should read the Information for UK recipients or contact their doctor or healthcare practitioner.

What is BNT162b2 and what is it used for?

BNT162b2 is a vaccine indicated for active immunisation to prevent COVID-19 caused by the SARS-CoV-2 virus, in individuals 12 years of age and older.

How does BNT162b2 work?

When a person is given BNT162b2, it triggers the body to naturally produce antibodies and stimulates immune cells to protect against COVID-19.

How is BNT162b2 used?

The pharmaceutical form of this medicine is an injection. Following dilution with saline, BNT162b2 is given to you by an authorised practitioner as an intramuscular injection into the muscle at the top of the upper arm (deltoid muscle). You should receive two doses (each 0.3mL) given 21 days apart.

For further information on how BNT162b2 is used, refer to the Information for UK Healthcare Professionals and the Information for UK recipients available on the Medicines and Healthcare products Regulatory Agency (MHRA) website.

This vaccine can only be obtained with a prescription.

If a person has any questions concerning the vaccine, they should ask the administering healthcare practitioner.

What benefits of BNT162b2 have been shown in studies?

BNT162b2 has been studied in approximately 43,000 individuals 16 years of age and older who were equally allocated to the vaccine or a placebo. Those who received vaccination with BNT162b2 had a reduction in the rate of COVID-19 illness compared to those who received placebo (8 cases of COVID-19 illness in the vaccinated group compared to 162 cases in the placebo group). These results were observed 7 days following the second dose in study participants with no evidence of prior SARS-CoV-2 infection.

A similar benefit of the vaccine was observed in subjects with one or more other medical conditions that increase the risk of severe COVID-19 disease, such as obesity, hypertension, diabetes, or asthma.

The most common side effects with BNT162b2 (which may affect more than 1 in 10 people) were pain at the injection site, tiredness, headache, muscle pain, chills, joint pain and fever. Adverse events were usually mild or moderate in intensity and resolved within a few days after vaccination.

Why was BNT162b2 approved?

It was concluded that BNT162b2 has been shown to be effective in the prevention of COVID-19. Furthermore, the side effects observed with use of this vaccine are considered to be similar to those seen with other vaccines. Therefore, the MHRA concluded that the benefits are greater than the risks and recommended that this medicine can be authorised for temporary supply during the COVID-19 pandemic.

What measures are being taken to ensure the safe and effective use of BNT162b2?

All new medicines approved require a Risk Management Plan (RMP) to ensure they are used as safely as possible. An RMP has been agreed for the use of BNT162b2 in the UK. Based on this plan, safety information has been included in the Information for UK Healthcare Professionals and the Information for UK recipients, including the appropriate precautions to be followed by healthcare professionals and patients.

All side effects reported by patients/healthcare professionals are continuously monitored. Any new safety signals identified will be reviewed and, if necessary, appropriate regulatory action will be taken. The MHRA has also put in place an additional proactive safety monitoring plan for all COVID-19 vaccines to enable rapid analysis of safety information which is important during a pandemic.

Other information about BNT162b2

Authorisation for the temporary supply of BNT162b2 was granted in the UK on 1 December 2020.

The full public assessment report for BNT162b2 follows this summary.

This summary was last updated in June 2021.

A marketing authorisation was granted for the Pfizer/BioNTech vaccine (Comirnaty) following a European Commission (EC) decision on 21 December 2020 (PLGB 53632/0002).

1. Introduction

This report is based on the information provided by the company in a rolling data submission procedure and it covers the authorisation for temporary supply of BNT162b2. At the time of writing, the main clinical study is still on-going and additional data is being collected. Due to differences in the collection date, the data and information in this report may differ from that contained in documents relating to BNT162b2 released by other regulatory authorities. Quality aspects of the vaccine are reviewed on a batch-specific basis.

In December 2019, a pneumonia outbreak of unknown cause occurred in Wuhan, China and in January 2020, a novel coronavirus was discovered as the underlying cause. Infections by the virus, named SARS-CoV-2, and the resulting disease, COVID-19, have spread globally. On 11 March 2020, the WHO declared the COVID-19 outbreak to be a pandemic.

At the time of this report, the number of COVID-19 cases in the UK is estimated at 1.64 million and more than 60,000 deaths have been attributed to the disease. These numbers continue to rise. The elderly and those with pre-existing medical conditions are at an increased risk of severe disease and death from COVID-19. Vaccination is the most effective medical intervention to decrease risk and reduce spread of the SARS-CoV-2 virus.

The Department of Health and Social Care (DHSC) is leading the Government’s deployment of vaccinations against COVID-19. In order to save lives, and to reduce the number of people who need hospital treatment due to COVID-19, the DHSC have sought to deploy a safe and effective vaccination as soon as possible. In a letter dated November 17th 2020, the DHSC requested authorisation, on a temporary basis, of its proposed supply of a vaccine manufactured by Pfizer/BioNTech collaboration, named “COVID-19 mRNA Vaccine BNT162b2”, under Regulation 174 of the Human Medicines Regulations 2012, (“the Regulations”).

Following an extensive review of the quality, safety and efficacy data, COVID-19 mRNA Vaccine BNT162b2 has been authorised for temporary supply in the UK for the following indication: active immunisation to prevent COVID-19 caused by SARS-CoV-2 virus, in individuals 16 years of age and older.

The active substance of the COVID-19 mRNA Vaccine BNT162b2 is a multi-dose concentrate of RNA-containing lipid nanoparticles formulated in saline and sucrose to be diluted for intramuscular (IM) administration. A single vial contains 5 doses of 30 micrograms of BNT162b2 RNA (embedded in lipid nanoparticles).

COVID-19 mRNA Vaccine BNT162b2 is highly purified single-stranded, 5’-capped messenger RNA (mRNA) produced by cell-free in vitro transcription from the corresponding DNA templates.

COVID-19 mRNA Vaccine BNT162b2 encodes a mutant viral spike (S) protein of SARS-CoV-2, with two point mutations inserted to lock S in an antigenically preferred prefusion conformation (P2 S). It is formulated as an RNA-lipid nanoparticle of nucleosidemodified mRNA containing N1-methylpseudouridine instead of uridine. Encapsulation into lipid nanoparticles enables transfection of the mRNA into host cells after intramuscular injection. During mixing of the RNA and the dissolved lipids, the lipids form the nanoparticles encapsulating the RNA. After injection, the lipid nanoparticles are taken up by the cells, and the RNA is released into the cytosol. In the cytosol, the RNA is translated into the encoded viral protein. The viral spike (S) protein antigen induces an adaptive immune response through neutralising antibodies. Furthermore, as the expressed spike (S) protein is being degraded intracellularly, the resulting peptides can be presented at the cell surface, triggering a specific T cell-mediated immune response with activity against the virus and infected cells.

The authorisation is for an identified batch of the vaccine (provided certain conditions are met), together with future batches, which will each be approved by MHRA on a batch-specific basis. These conditions are published on the MHRA website.

The MHRA has been assured that acceptable standards of Good Manufacturing Practice (GMP) are in place for this product at all sites responsible for the manufacture, assembly and batch release of this product.

A Risk Management Plan (RMP) and a summary of the pharmacovigilance system have been provided with this application and are satisfactory.

This batch, and any future batches, of COVID-19 mRNA Vaccine BNT162b2 are subject to Qualified Person (QP) certification and batch evaluation by an independent control laboratory before the vaccine is released into the UK.

The COVID-19 Vaccine Benefit Risk Expert Working Group (Vaccine BR EWG) have met several times to review and discuss the quality, safety and efficacy aspects in relation to batches of COVID-19 mRNA Vaccine BNT162b2. The manufacturer, Pfizer/BioNTech, was also invited to a separate meeting with the quality subgroup of the Vaccine BR EWG to review and discuss questions related to manufacture and control of the product.

The Vaccine BR EWG gave advice to the Commission of Human Medicines (CHM) on 11th September 2020, 8th October 2020, 27th October 2020, 28th November 2020 and 30th November 2020, regarding the requirements for authorisation for the temporary supply of COVID-19 mRNA Vaccine BNT162b2. The requirements for quality, safety and efficacy were considered, taking into account the urgent public health need and risk to life, the pandemic situation and a lack of COVID-19 vaccines. As well as data on quality, safety and efficacy, specific mitigations and conditions on the product were discussed to ensure adequate standards of quality and safety are met.

The CHM concluded that the proposed supply of COVID-19 mRNA Vaccine BNT162b2 for active immunisation to prevent COVID-19 caused by SARS-CoV-2 virus, in individuals 16 years of age and older, is recommended to be suitable for approval under Regulation 174 provided the company meets the conditions set out by the MHRA.

Authorisation for the temporary supply of COVID-19 mRNA Vaccine BNT162b2 was granted in the UK on 1 December 2020. This report covers data received and reviewed for this authorisation only. This authorisation is valid until expressly withdrawn by MHRA or upon issue of a marketing authorisation.

Whilst an acceptable level of information has been received to provide assurance that appropriate standards of quality, safety and efficacy have been met for authorisation of specific batches for temporary supply under Regulation 174 of the Regulations, it should be noted that COVID-19 mRNA Vaccine BNT162b2 remains under review as MHRA continues to receive data from the company as it becomes available. This will include, for example, long-term follow-up efficacy and safety data. Further information that is received by the MHRA will be reviewed as part of the ongoing assessment for this product and updates will be made to this PAR to reflect that in due course.

On 4 June 2021 the MHRA granted an extension of indication to ‘the active immunisation to prevent COVID-19 caused by the SARS-CoV-2 virus, in individuals 12 years of age and older’.

2. Quality aspects

2.1 Introduction

This product is a white to off-white solution provided in a multidose vial and must be diluted before use. One vial contains 5 doses of 30 micrograms of BNT162b2 RNA embedded in lipid nanoparticles (LNPs). COVID-19 mRNA Vaccine BNT162b2 is provided in a pack size of 195 vials.

COVID-19 mRNA Vaccine BNT162b2 is highly purified single-stranded, 5’-capped messenger RNA (mRNA) in lipid nanoparticles (LNPs). The mRNA is produced by cell-free in vitro transcription from the corresponding DNA templates, encoding the viral spike (S) protein of SARS-CoV-2.

In addition to BNT162b2 RNA this product also contains the excipients ALC-0315 = (4- hydroxybutyl) azanediyl)bis (hexane-6,1-diyl)bis(2-hexyldecanoate), ALC-0159 = 2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide, 1,2-Distearoyl-sn-glycero-3 phosphocholine, cholesterol, potassium chloride, potassium dihydrogen phosphate, sodium chloride, disodium hydrogen phosphate dihydrate, sucrose and water for injections.

The finished product is packaged in a 2 mL clear vial (type I glass) with a stopper (coated bromobutyl) and a plastic flip-off cap with aluminium seal. Container closure components comply with the relevant regulatory requirements. Satisfactory specifications and Certificates of Analysis have been provided for all packaging components. All primary packaging complies with the current Ph. Eur. quality standards

2.2 Active substance

Drug Substance (BNT162b2 RNA)

BNT162b2 drug substance is a single-stranded, 5’-capped mRNA encoding the full-length viral S (S1S2) protein of SARS-CoV-2. The optimised codon sequence encoding the spike glycoprotein antigen of the SARS-CoV-2 virus results in a protein expressed with two proline mutations that fix the S1S2 spike protein in a pre-fusion conformation to increase potential to elicit virus neutralising antibodies. In addition, the RNA contains common structural elements optimised for mediating high RNA stability and translational efficiency (5’-cap, 5’-UTR, 3’-UTR, poly(A) – tail). Uridine is replaced by modified N1- methylpseudouridine (m1ΨTP) in the RNA synthesis which increases RNA persistence invivo through dampening of innate immune response to itself. The 5 prime end is capped with a structure which will not activate the innate immune system.

Chemical Name: messenger RNA (mRNA), 5’-capped, encoding a full-length, codonoptimised pre-fusion stabilised conformation variant (K986P and V987P) of the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2, GenBank: MN908947.3) spike (S) glycoprotein, flanked by 5’ and 3’ untranslated regions and a 3’ poly(A) tail; contains N1-methylpseudouridine instead of uridine (all-U>m1 Ψ). Immunological agent for active immunisation (anti-SARS-CoV-2)

Appearance: Clear to slightly opalescent, colourless to slightly brown liquid

BNT162b2 RNA is not the subject of a European Pharmacopoeia monograph (Ph. Eur.) or other pharmacopoeial monograph.

Overall, production of the active substance from the designated starting materials has been adequately described and appropriate in-process controls and adequate starting material specifications are applied.

The starting materials are adenosine triphosphate, cytidine triphosphate, guanosine triphosphate, modified uridine triphosphate, 5’ Cap and the DNA template from which the RNA is transcribed.

The DNA template from which the RNA is transcribed is critical for the fidelity of the mRNA. The manufacture of the DNA template has been described. It is manufactured through fermentation in an established and well-controlled Escherichia coli cell line, extracted and purified. The specifications controlling the quality of the DNA template are satisfactory. Batch data for the DNA template have been supplied for several batches for which an acceptable level of batch to batch consistency is observed. The genealogy of the finished product can be traced back to the batch of originating DNA template.

The in vitro enzymatic RNA transcription process has been adequately described. The 5’cap and poly(A) tail are co-transcribed with the S1S2 spike protein codon. It is noted that the operating parameters for this process span a wide range however this does not raise any immediate concerns for the batch under review.

Full scale validation data for RNA transcription demonstrates consistency and repeatability of the process operation and is accepted as qualifying the process operated at its target set points.

The manufacturer has performed a comparability assessment of drug substance batches used in the clinical trial programme and batches representative of the subsequent manufacturing changes occurring during product development, such as introduction of new manufacturing sites, manufacturing process changes and increase in batch scale, including full scale validation batches. The drug substance batch release data for essential parameters that control the quality of the active RNA and several extended characterisation test parameters were considered. These data demonstrate consistency between the drug substance described for this application and those used in the pivotal clinical study.

Analytical procedure methods have been described and are considered appropriately qualified to control this batch in the context of a batch specific approval.

The shelf-life for BNT162b2 RNA (drug substance) has been provided and is satisfactory in relation to the cadence of drug substance to drug product manufacture.

2.3 Drug product

The data submitted to describe the drug product have been evaluated.

Pharmaceutical development

The manufacturer has described the finished product development strategy. This utilised principles described in ICH Q8 Pharmaceutical Development and was based on the available scientific knowledge and the manufacturer’s prior experience with similar RNA-lipid nanoparticle vaccines, as well as risk assessments and development studies.

The characteristics of the drug product were provided, as well as formulation development and process characterisation studies. The development history, including process changes have been summarised. The manufacturer has described their approach to defining critical quality attributes and the rationale for their criticality decisions, as well as their process risk assessment strategy and methodology, which was accompanied by a description of the manufacturer’s product development and characterisation strategy. Operating ranges have been defined and the manufacturer is working on the validation of the final commercial process, which follows process optimisation.

A quality target product profile for the finished product has been established taking into consideration the World Health Organization’s WHO Target Product Profiles for COVID19 Vaccines.

Development studies have been submitted which support the compatibility of the vaccine with the container closure and the unpreserved sodium chloride 0.9% diluent as well as commonly used needles and syringes.

The manufacturer has performed a comparability assessment of batches used in the clinical trial programme and batches representative of manufacturing changes occurring during product development, such as introduction of new manufacturing sites, process changes and increase in batch scale. In addition to release testing, the manufacturer also investigated several extended characterisation test parameters. These data will be supplemented as further experience with the manufacturing process accumulates. The recommendation for the batch which is the subject of this assessment was based on a direct comparison of the batch release results with the results for the clinically qualified batches.

Manufacture of the product

A description of the manufacturing method for COVID-19 mRNA Vaccine BNT162b2 has been provided and consists of: thawing and dilution of the drug substance, lipid nanoparticle formation upon mixing organic and aqueous phases (where specialised equipment is used for LNP formation), buffer exchange, concentration, filtration, formulation, sterile filtration, aseptic filling, visual inspection, labelling and freezing, and storage packaging and shipment.

In-process monitoring and control are performed. In-process controls and process parameters for each manufacturing step are provided and criticality has been assigned. Further in-process details are expected from the manufacturer however the information provided to date are acceptable.

As part of the control of the product, once vials are manufactured, they undergo 100% visual inspection for defects.

A condition of authorisation under this regulation is that the manufacturer will provide further data on the drug product manufacturing process as it is scaled up.

Excipients

The excipients sucrose, sodium chloride, potassium chloride, dibasic sodium phosphate dihydrate, monobasic potassium phosphate and water for injection are all of Ph. Eur. grades, which are acceptable.

In addition to those excipients, the vaccine contains four lipids, of which two are used in approved medicinal products (cholesterol and 1,2-distearoyl-sn-glycero-3-phosphocholine, hereafter termed DSPC) and two are considered novel in that they have not been used in an authorised medicinal product in the UK:

  • ALC-0315 ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate))
  • ALC-0159 (2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide).

The lipids are intended to encapsulate the mRNA in the form of a lipid nanoparticle to aid cell entry and stability of the RNA/lipid nanoparticles.

ALC-0315 is the functional cationic lipid component of the drug product. When incorporated in lipid nanoparticles, it helps regulate the endosomal release of the RNA. During drug product manufacturing, introduction of an aqueous RNA solution to an ethanolic lipid mixture containing ALC-0315 at a specific pH leads to an electrostatic interaction between the negatively charged RNA backbone and the positively charged cationic lipid. This electrostatic interaction leads to encapsulation of RNA drug substance resulting with particle formation. Once the lipid nanoparticle is taken up by the cell, the low pH of the endosome renders the LNP fusogenic and allows the release of the RNA into the cytosol.

The primary function of the PEGylated lipid ALC-0159 is to form a protective hydrophilic layer that sterically stabilises the LNP which contributes to storage stability and reduces nonspecific binding to proteins. As higher PEG content can reduce cellular uptake and interaction with the endosomal membrane, PEG content is controlled.

Cholesterol is included in the formulation to support bilayer structures in the lipid nanoparticle and to provide mobility of the lipid components within the lipid nanoparticle structure. The specification for the conventional lipid, cholesterol, is considered acceptable for the purpose of this application.

DSPC is a phospholipid component intended to provide a stable bilayer-forming structure to balance the non-bilayer propensity of the cationic lipid. DSPC is a non-pharmacopeial excipient and an adequate specification has been provided.

The controls in place for the excipients are considered suitable for this application.

Excipients of human and animal origin

No excipients of animal or human origin are used in the finished product.

Novel excipients

ALC-0315 is a cationic lipid and is critical to the self-assembly process of the particle itself, the ability of the particle to be taken up into cells and the escape of the RNA from the endosome. ALC-0159 is a polyethylene glycol (PEG) lipid conjugate (i.e. PEGylated lipid).

Finished product control

The product specification includes relevant control parameters considering the nature of the product and its manufacturing process.

Batch release data for this batch have been evaluated comparing the results with the clinically qualified ranges from batches used in the clinical trial programme.

Independent batch testing

Independent batch testing is required for vaccines and provides additional assurance of quality before a batch is made available to the market. Independent batch testing is a function that is undertaken by an Official Medicines Control Laboratory (OMCL) and, under Regulation 174A, the UK’s National Institute for Biological Standards and Control (NIBSC) is responsible for this function. Each batch will be independently tested prior to deployment.

Independent batch testing is product-specific and highly technical: it requires specific materials and documentation from the manufacturer and comprises laboratory-based testing and review of the manufacturer’s test data. If all tests meet the product specifications a certificate of compliance is issued by the OMCL.

Characterisation of impurities

The impurity profile of the BNT162b2 drug product is based primarily on the impurity profile of the materials used for its manufacture.

The manufacturer has described four identified drug product manufacturing process-related impurities. A safety risk assessment for each of these four potential impurities has been performed and they are below the safety threshold given the intended product administration schedule.

Process-impurities from the sucrose, phosphate and chloride salts used in the final drug product formulation are controlled through testing and specifications ensuring compliance to relevant compendial monographs. This is acceptable.

The lipid impurities are controlled through the acceptance criteria used for their manufacture.

No critical issues have been identified with respect to the lipids that would preclude the emergency use of the vaccine.

Reference standards or materials

The manufacturer has defined reference materials that are used in the determination of drug product content and in the determination of lipid content for the four lipids used for nanoparticle formation. These methods are considered conventional and uncomplicated to perform.

Container closure system

Overall, the container closure system has been well described and complies with the relevant quality standards of the Ph.Eur. The vaccine requires storage at ultra-low temperature conditions and the rubber septum is punctured at least 6 times to reconstitute the product and recover 5 doses from the vial. The manufacturer has provided details of adequate testing to provide evidence that the self-sealing capacity of the elastomeric closure is retained upon freezing and repeated thawing of product, even though the storage requirements do not permit this. The testing also accounted for the recommended needles for diluent addition.

Stability

The manufacturer has provided all stability data available to date. Information on the stability of batches used in clinical trials has been used to support conclusions on product storage and storage conditions.

Based on the stability information currently available, a shelf-life of 6 months at -80°C to -60°C can be accepted for this vaccine, with the following storage conditions:

  • Store in a freezer at -80°C to -60°C
  • Store in the thermal container at -90ºC to -60ºC

Store in the original package in order to protect from light.

After removal from frozen storage, the undiluted vaccine can be stored for up to 5 days (120 hours) at 2°C to 8°C and up to 2 hours at temperatures up to 25°C, prior to use. Once thawed, the vaccine cannot be re-frozen.

During storage, it is recommended that exposure to room light is minimised, and exposure to direct sunlight and ultraviolet light avoided. Thawed vials can be handled in room light conditions.

After dilution with unpreserved normal saline, the vaccine should be stored at 2°C to 25°C and used as soon as practically possible. Since the vaccine does not contain a preservative, once the stopper has first been punctured on addition of the diluent, the vial should be used within 6 hours as is recommended by WHO guidance. After 6 hours, any unused vaccine left in the vial should be discarded.

Deployment of this vaccine is subject to the conditions of this Regulation 174 approval.

Suitable post approval stability commitments have been provided to continue stability testing on batches of COVID-19 mRNA Vaccine BNT162b2, including for the batch concerning this Regulation 174 application. The manufacturer has committed to provide these data to the MHRA on an on-going basis as it becomes available.

Handling of Pfizer Vaccine BNT162b2

Lipid nanoparticles (LNPs) are complex particles made of four lipid components that entrap the mRNA. Because of this complexity LNPs are potentially fragile to degradation and damage through inappropriate handling.

The published storage conditions are qualified by the data reviewed by the MHRA.

  • Long term storage: It must be stored frozen at ultra-low temperature (ULT).

After removal from frozen storage, it has a shelf life of up to 120 hours at 2-8 ºC before being diluted (label to be added once box removed from freezer).

In addition to the 120-hour period at 2-8 ºC, an undiluted vial can be stored for 2 hours at up to 25 ºC. This is intended to qualify removing the vial from the fridge for up to two hours immediately before it is diluted in preparation for use. It is not intended to qualify ad hoc removal from fridge within the 120-hour period with a view to then replacing back into stock were it not to be used.

Once thawed, the vaccine cannot be refrozen.

Before dilution the vial must be inverted gently 10 times without shaking (to avoid foaming). Once the specified diluent is added, the vial must be inverted gently 10 times without shaking (to avoid foaming).

Once diluted, the vials should be marked with the dilution date and time.

Transportation by motor vehicle of diluted vaccine away from the site of dilution is not currently supported by any relevant stability data.

After dilution the vaccine should be used as soon as is practically possible and within 6 hours of dilution; it can be stored at 2-25 ºC during this period. It would not normally be considered good practice to store diluted product for 6 hours at 25ºC before being administered.

Similarly, there are no data supporting multiple temperature cycling within that 6 hours that would qualify the product being repeatedly removed and replaced into a fridge, as doses are administered over the course of 6 hours.

Following dilution, vials should be used in the shortest time period possible.

2.4 Regulation 174

Authorisation for temporary supply of COVID-19 mRNA Vaccine BNT162b2 under this Regulation 174 has been given following review of batch analytical data by MHRA.

Independent batch release by the National Institute for Biological Standards and Control (NIBSC) will be performed on all batches to be supplied to the UK.

The quality data currently available for COVID-19 mRNA Vaccine BNT162b2 can be accepted as sufficient with specific conditions in place. There are no scientific objections arising from this review to the authorisation for temporary supply for this product under Regulation 174 of the Human Medicine Regulations.

3. Non-clinical aspects

3.1 Introduction

COVID-19 mRNA Vaccine BNT162b2 has been developed for use in healthy subjects to prevent COVID-19 on exposure to SARS-CoV-2. The vaccine has as its active agent messenger ribonucleic acid (mRNA), made by transcription of a DNA template, encoding for the full-length spike (S) protein of SARS CoV-2 with two point mutations, to lock S in an antigenically preferred prefusion conformation.

COVID-19 mRNA Vaccine BNT162b2 is given as two intramuscular injections (IM), 21 days apart, of the same dose of 30 μg mRNA.

COVID-19 mRNA Vaccine BNT162b2 is made up of the mRNA component with 4 lipid components forming nanoparticles, of which two are novel and not used before in pharmaceutical products in the UK. The lipids function to encapsulate, stabilise the mRNA and mediate its delivery to cells.

The following non-clinical studies were submitted with this application:

Pharmacology

  • Study 20-0211: In vitro expression of BNT162b2 drug substance and drug product
  • Study R-20-0085: COVID-19: Immunogenicity of BNT162b2 in mice
  • Study R-20-0112: Characterizing the immunophenotype in spleen and lymph node of mice treated with SARS-CoV-2 vaccine candidates
  • Study VR-VTR-10671: BNT162b2 immunogenicity and evaluation of protection against SARS-CoV-2 challenge in rhesus macaques

Pharmacokinetics

  • Study PF-07302048: Single dose pharmacokinetics study of ALC-0315 and ALC-0159 following intravenous bolus injection of a nanoparticle formulation in rats
  • Study R-20-0072: Biodistribution of BNT162b2 using the luciferase protein as a surrogate marker protein after intramuscular injection in mice. Toxicology
  • Study 38166: Repeat-dose toxicity study of three LNP-formulated RNA platforms encoding for viral proteins by repeated intramuscular administration to Wistar Han rats
  • Study 20GR142: 17-day Intramuscular Toxicity Study of BNT162b2 and BNT162b3 in Wistar Han Rats

These studies were conducted in accordance with current Good Laboratory Practice (GLP).

3.2 Pharmacology

This vaccine acts by intracellular translation of mRNA to the SARS-CoV-2 S protein to induce an immune response, a humoral neutralizing antibody response and Th1-type CD4+ and CD8+ cellular response, to block virus infection and kill virus infected cells, respectively.

The vaccine was tested for its ability to result in S protein expression in a mammalian cell population in vitro, for its immunogenicity in mice in two studies, and in one study in rhesus monkeys, including its capacity to prevent disease after challenge with SARS Cov-2 virus in rhesus monkeys. The vaccine also induced an immune response in rats in the two toxicity studies.

Study 20-0211 analysed SARS-CoV-2 P2 S expression in HEK293T cells. The initial demonstration of in vitro expression in HEK293 cells confirmed that transfection and subsequent protein expression could take place, including in cells incubated with the nanoparticle presentation of the vaccine.

In Study R-20-085, four groups of eight female mice were immunised once by the IM route on day 0 with 0.2 µg, 1 µg or 5 µg RNA/animal of COVID-19 mRNA Vaccine BNT162b2, or with a control. Antibody response was assessed at days 7, 14, 21 and 28.

Study R-20-0112 aimed to characterise T- and B-cell responses in the spleen, lymph nodes and blood of BNT162b2 immunised mice. It characterised changes in the myeloid cell compartment, determined the ability of CD8+ T-cells to react to cells presenting the vaccineencoded antigen, and determined antibody responses.

In Studies R-20-085 and R-20-0112 in mice, a dose-response effect was seen in the IgG responses specific for the SARS CoV-2 S1 protein fragment and its receptor binding domain.

A high and dose-dependent pseudovirus neutralising antibody response was confirmed. CD4+ and CD8+ T cell cellular responses with a Th1 pattern of response (e.g. production of IFN-γ) were observed. Booster responses were not evaluated in these studies.

Study VR-VTR-10671 was performed in male rhesus macaques aged 2-4 years vaccinated with 30 μg COVID-19 mRNA Vaccine BNT162b2, 100 μg COVID-19 mRNA Vaccine BNT162b2 or a control.

Results showed COVID-19 mRNA vaccine BNT162b2 was immunogenic, eliciting IgG responses after a single dose, which were boosted by a second dose. It also showed a dose response. At 30 μg BNT162, the neutralising geometric mean titre in a SARS-CoV-2 neutralization assay was compared to that seen in convalescent serum (HCS) from humans recovered from SARS CoV-2 infection/COVID-19 and found to be ~8-times higher. Seven days after Dose 2 of 100 μg, the neutralising GMT reached 18-times that of the HCS panel and remained 3.3-times higher than this benchmark five weeks after the last immunisation. In monkeys, the cellular immune response was characterised as a strongly Th1-biased CD4+ T cell response with a concurrent interferon-γ (IFNγ)+ CD8+ T cell response.

For the challenge portion of the study, SARS-CoV-2 challenge was performed on the COVID-19 mRNA Vaccine BNT162b2-immunised animals (100 µg/animal dose level) and on animals dosed with a control. Upon challenge with SARS CoV-2, the resulting clinical pattern in monkeys was unremarkable and no signs of clinical illness resulted from this exposure. Total viral RNA (genomic and subgenomic RNA) was detected in bronchoalveolar lavage fluid of control monkeys but not detected in monkeys immunised with BNT162b2; in the nasal swabs viral RNA was detected in monkeys given BNT162 but clearance was faster than in controls. This is evidence of the beneficial effect of this vaccine. In lung tissues, control monkeys had evidence of some pulmonary disease indicated by their increased scores on computed tomography scans with a suggestion of recovery in those scores at day 10 that were less than those at day 3; in contrast, the monkeys given COVID-19 mRNA Vaccine BNT162b2 had lower scores than controls.

The absence of secondary pharmacology and safety pharmacology studies is acceptable for a vaccine and is in line with relevant regulatory guidance (WHO Guidelines on nonclinical evaluation of vaccines, 2005). The guidance does not mention secondary pharmacodynamics: however, it does state that if data from other studies suggest that the vaccine may affect physiological functions (central nervous system, renal, respiratory or cardiovascular system functions), safety pharmacology studies should be incorporated into the toxicity assessment. This does not apply for COVID-19 mRNA Vaccine BNT162b2.

There are no major public health concerns identified. Since this authorisation the manufacturer has provided further information on the methodology used to determine antispike protein antibodies in mice which has been reviewed as part of the ongoing assessment for this product. These data are not discussed here.

3.3 Pharmacokinetics

The active substance of COVID-19 mRNA Vaccine BNT162b2 is N1-methylpseudouridine instead of uridine containing mRNA expressing full-length SARS-CoV-2 spike protein with two proline mutations (P2 S) to lock the transmembrane protein in an antigenically optimal prefusion conformation. The vaccine is formulated in lipid nanoparticles (LNPs). The LNP is composed of 4 lipids: ALC-0315, ALC-0159, 1,2-distearoyl-sn-glycero-3-phosphocoline (DSPC), and cholesterol. Of the four lipids used as excipients in the LNP formulation, two are naturally occurring (cholesterol and DSPC) and will be metabolised and excreted like their endogenous counterparts.

Pharmacokinetic studies have not been conducted with COVID-19 mRNA Vaccine BNT162b2 and are generally not considered necessary to support the development and licensure of vaccine products for infectious diseases (WHO, 2005; WHO, 2014).

The ADME profile of COVID-19 mRNA Vaccine BNT162b2 included evaluation of the PK and metabolism of the two novel lipid excipients (ALC-0315 and ALC-0159) in the LNP and potential in vivo biodistribution using luciferase expression as a surrogate reporter.

Absorption

No absorption studies were conducted for COVID-19 mRNA Vaccine BNT162b2 since the route of administration is intramuscular (IM).

The “Single dose pharmacokinetics study of ALC-0315 and ALC-0159 following intravenous bolus injection of a nanoparticle formulation in rats” was conducted to assess the PK and metabolism of the two novel lipid excipients (ALC-0315 and ALC-0159). This study used LNPs containing surrogate luciferase RNA, with the lipid composition being identical to BNT162b2, to investigate the in vivo disposition of ALC-0159 and ALC-0315.

Concentrations of ALC-0159 dropped approximately 8000- and >250-fold in plasma and liver, respectively, during this 2-week study. For ALC-0315, the elimination of the molecule from plasma and liver was slower, but concentrations fell approximately 7000- and 4-fold in two weeks for plasma and liver, respectively. Overall, the apparent terminal t½ in plasma and liver were similar in both tissues and were 2-3 and 6-8 days for ALC-0159 and ALC0315, respectively. The apparent terminal t½ in plasma likely represents the re-distribution of the respective lipids from the tissues into which they have distributed as the LNP, back to plasma where they are eliminated.

Distribution

Study R-20-0072 evaluated the in vivo potential biodistribution of COVID-19 mRNA Vaccine BNT162b2 in mice using luciferase expression as a surrogate reporter. Protein expression was demonstrated at the site of injection and to a lesser extent, and more transiently, in the liver after mice received an IM injection of RNA encoding luciferase in an LNP formulation like BNT162b2. Luciferase expression was identified at the injection site at 6 hours after injection and diminished to near baseline levels by day 9. Expression in the liver was also present at 6 hours after injection and was not detected by 48 hours after injection. Information regarding the potential distribution of the test articles to sites other than the injection site following IM administration has been provided and is under review as part of the ongoing rolling assessment.

Metabolism

The in vitro metabolism of ALC-0315 and ALC-0159 was evaluated in blood, liver microsomes, S9 fractions, and hepatocytes from mice, rats, monkeys, and humans. The in vivo metabolism was examined in rat plasma, urine, faeces, and liver samples from the PK study. Metabolism of ALC-0315 and ALC-0159 appears to occur slowly in vitro and in vivo. ALC-0315 and ALC-0159 are metabolised by hydrolytic metabolism of the ester and amide functionalities, respectively, and this hydrolytic metabolism is observed across the species evaluated.

Excretion

No excretion studies have been conducted with COVID-19 mRNA Vaccine BNT162b2. In the PK study, it appears that 50% of ALC-0159 was eliminated unchanged in faeces. Metabolism played a role in the elimination of ALC-0315, as little to no unchanged material was detected in either urine or faeces. Investigations of urine, faeces and plasma from the rat PK study identified a series of ester cleavage products of ALC-0315. The manufacturer has proposed that this likely represents the primary clearance mechanism acting on this molecule, although no quantitative data is available to confirm this hypothesis. In vitro, ALC-0159 was metabolised slowly by hydrolytic metabolism of the amide functionality.

Pharmacokinetic drug interactions

No PK drug interaction studies have been conducted with COVID-19 mRNA Vaccine BNT162b2. This is acceptable and in line with relevant guidelines (WHO 2005; WHO 2014).

3.4 Toxicology

Single dose toxicity

No single dose toxicity studies have been performed. This is acceptable and in line with relevant guidelines (WHO 2005; WHO 2014).

Repeat-dose toxicity

Study 38166 was a GLP-compliant repeat-dose study performed in rats to evaluate toxicity of the LNP and mRNA platform used in BNT162b2.

Study 20GR142 was a GLP-compliant repeat-dose study performed in rats to evaluate toxicity of COVID-19 mRNA Vaccine BNT162b2.

In Study 38166, male and female Wistar rats were given BNT162b2 as IM injection(s) into the hind limb on three occasions each a week apart (dosing days 1, 8 and 15). Different doses (10, 30, and 100 μg) were tested; the lower doses were given as a single injection of 20-70 μL, while the highest dose (100 μg) and controls were given as two injections (one in each hindlimb) of 100 μL each. The control was phosphate buffered saline/300 mM sucrose, corresponding to the storage buffer of the vaccine product. Each group had 18 male and 18 female rats, assigned as 10 to the main study, 5 for recovery groups and 3 as additional animals for cytokine analyses. The recovery period was 3 weeks after the last dose. Necropsy was performed on study day 17, ~48 hours after the last dose, and after the 3-week recovery period.

No unscheduled deaths were observed.

Dosing was considered well tolerated and did not present any signs of systemic toxicity; there was a slight increase in body temperature in the hours after dosing and some loss in body weight over the same period but these were not of a magnitude to be considered adverse.

Local inflammatory reactions were observed at the intramuscular injection site. Injection site changes noted were of oedema, erythema, and induration, more severe and more frequent after the second and/or third doses compared to the first; however, these resolved prior to subsequent dosing and were fully recovered at the end of the 3-week recovery period.

Macroscopic findings at the injection sites included induration or thickening, occasionally accompanied by encrustation, which was noted for nearly all rats. This correlated microscopically with inflammation and variable fibrosis, oedema, and myofibre degeneration. Inflammation at the injection site was accompanied by elevations in circulating white blood cells and acute phase proteins (fibrinogen, alpha-2 macroglobulin, and alpha-1 acid glycoprotein).

Inflammation was occasionally evident extending into tissues adjacent to the injection site. There was enlargement of the draining (iliac) lymph nodes evident at the end of dosing. This correlated with increased cellularity of germinal centres and increased plasma cells in the draining (iliac) lymph node and is an anticipated immune response to the administered vaccine.

Enlargement of spleen and increased spleen weights correlated microscopically to increased haematopoiesis and increased haematopoiesis was also evident in the bone marrow. These findings are likely secondary to the immune/inflammatory responses to the vaccine.

At the end of the recovery period, injection sites were normal, clinical pathology findings and macroscopic observations had resolved and there was evidence of recovery of the injection site inflammation on microscopy.

Microscopic vacuolation of portal hepatocytes was present. There were no elevations in alanine aminotransferase (ALAT). There were elevations in gamma-glutamyltransferase (GGT) in all vaccinated rats, but there were no macroscopic or microscopic findings consistent with cholestasis or hepatobiliary injury to explain the increased GGT activity, which was completely resolved at the end of the 3-week recovery period.

The vacuolation may be related to hepatic distribution of the pegylated lipid in the LNP. No changes were seen in serum cytokine concentrations. Additional ADME data has been received since this authorisation and has been reviewed as part of the ongoing assessment for this product. This data is not discussed here.

There were no effects noted on ophthalmological and auditory assessments, nor on external appearance or behaviour; in particular, gait was normal meaning that the changes seen did not affect the rats’ mobility. No vaccine-related changes were seen in serum cytokine concentrations.

Testing for immunogenicity showed that COVID-19 mRNA Vaccine BNT162b2 elicited a specific IgG antibody response to SARS CoV-2 spike protein directed against the S1 fragment and the receptor binding domain. A neutralizing antibody response was also observed with the vaccine in a pseudovirus neutralization assay.

In conclusion, COVID-19 mRNA Vaccine BNT162b2 was well tolerated, and produced inflammatory changes at the injection sites and the draining lymph nodes, increased haematopoiesis in the bone marrow and spleen, and clinical pathology changes consistent with an immune response or inflammation in the injection sites. The findings in this study are typical of those expected with dosing of LNP encapsulated mRNA vaccines.

Study 20GR142 had the objective to determine toxicity in rats given COVID-19 mRNA Vaccine BNT162b2. This study was in compliance with Good Laboratory Practice. Two candidate vaccines were tested; however, results are presented here only for COVID-19 mRNA Vaccine BNT162b2.

Male and female Wistar Han rats were given BNT162b2 as an IM injection into the hind limb on three occasions, each a week apart (dosing days 1, 8 and 15). Necropsy was performed on study day 17, ~48 hours after the last dose, and after the 3-week recovery period. COVID-19 mRNA Vaccine BNT162b2 was supplied at 0.5 mg/ml, and the dose volume was 60 μL, to give 30 μg per dose. Control rats received saline. Each group contained 15 males and 15 females.

All rats given COVID-19 mRNA Vaccine BNT162b2 survived to their scheduled necropsy: there were no changes noted in clinical signs or body weight changes noted. A reduction in food intake was noted on days 4 and 11 (to 0.83x controls) and there was an increase in mean body temperature post-dose on day 1 (up to 0.54°C), day 8 (up to 0.98°C) and day 15 (up to 1.03°C) compared to controls.

At injection sites, there were instances of oedema and erythema on days 1 (maximum of slight oedema and very slight erythema), 8 (maximum of moderate oedema and very slight erythema) and 15 (maximum of moderate oedema and very slight erythema) which fully resolved and were not noted prior to dosing on days 8 and 15.

Haematological tests showed higher white blood cells (up to 2.95x controls), primarily involving neutrophils (up to 6.80x controls), monocytes (up to 3.30x controls), and large unstained cells, LUC, (up to 13.2x controls) and slightly higher eosinophils and basophils on days 4 and 17. White blood cells were higher on day 17 as compared with day 4. There were transiently lower reticulocytes on day 4 (to 0.27x controls) in both sexes and higher reticulocytes on day 17 (up to 1.31x controls) in females only. Lower red blood cell mass parameters (to 0.90x controls) were present on days 4 and 17. There were lower A:G ratios (to 0.82x) on days 4 and 17. Higher fibrinogen was noted on day 17 (up to 2.49x) compared to controls, consistent with an acute phase response. The acute phase proteins alpha-1-acid glycoprotein (up to 39x on day 17) and alpha-2 macroglobulin (up to 71x on Day 17) were elevated on days 4 and 17 with higher concentrations in males. There were no changes urinalysis parameters.

At post-mortem there were higher absolute and relative spleen weights in vaccinated rats (up to 1.42x in males and to 1.62x in females). There were no other changes in organ weights. Macroscopic findings included enlarged draining lymph nodes and pale/dark firm injection sites in a minority of vaccinated rats. The dosing is reported as tolerated without inducing any systemic toxicity and with all changes consistent with an inflammatory response and immune activation: findings are consistent with those typically associated with dosing of lipid nanoparticle-encapsulated mRNA vaccines. Since this authorisation the manufacturer has provided the final study report which has been reviewed as part of the ongoing assessment for this product and is not discussed here.

Toxicokinetics

No toxicokinetic studies have been performed with the vaccine. This is consistent with WHO guidelines on the nonclinical evaluation of vaccines (WHO 2005).

Genotoxicity

No genotoxicity studies are planned for BNT162b2, as the components of all vaccine constructs are lipids and RNA that are not expected to have genotoxic potential (WHO, 2005).

Carcinogenicity

Carcinogenicity studies with BNT162b2 have not been conducted as the components of all vaccine constructs are lipids and RNA that are not expected to have carcinogenic or tumorigenic potential. Carcinogenicity testing is generally not considered necessary to support the development and licensure of vaccine products for infectious diseases (WHO, 2005).

Reproductive and developmental toxicity

Fertility and early embryonic development and embryofoetal development

In the general toxicity studies, macroscopic and microscopic evaluation of male and female reproductive tissues showed no evidence of toxicity.

A combined fertility and developmental study (including teratogenicity and postnatal investigations) in rats is ongoing.

Prenatal and postnatal development, including maternal function

No such studies have been done.

Studies in which the offspring (juvenile animals) are dosed and/or further evaluated

No such studies have been done.

Local tolerance

No such studies have been done. The assessments made as part of the general toxicity study should suffice and a separate study is not needed.

Other toxicity studies

No such studies have been done.

Toxicity conclusions

The absence of reproductive toxicity data is a reflection of the speed of development to first identify and select COVID-19 mRNA Vaccine BNT162b2 for clinical testing and its rapid development to meet the ongoing urgent health need. In principle, a decision on licensing a vaccine could be taken in these circumstances without data from reproductive toxicity studies animals, but there are studies ongoing and these will be provided when available. In the context of supply under Regulation 174, it is considered that sufficient reassurance of safe use of the vaccine in pregnant women cannot be provided at the present time: however, use in women of childbearing potential could be supported provided healthcare professionals are advised to rule out known or suspected pregnancy prior to vaccination. Women who are breastfeeding should also not be vaccinated. These judgements reflect the absence of data at the present time and do not reflect a specific finding of concern. Adequate advice with regard to women of childbearing potential, pregnant women and breastfeeding women has been provided in both the Information for UK Healthcare Professionals and the Information for UK recipients.

3.5 Ecotoxicity/Environmental Risk Assessment

It is agreed that, in accordance with CHMP guidance EMEA/CHMP/SWP/4447100 entitled, “Guideline on the Environmental Risk Assessment of Medicinal Products for Human Use” published 01 June 2006, due to their nature, vaccines and lipids are unlikely to result in a significant risk to the environment. Therefore, an environmental risk assessment is not provided in this application. This is acceptable.

3.6 Discussion and conclusion on the non-clinical aspects

The non-clinical data currently available for COVID-19 mRNA Vaccine BNT162b2 can be accepted as sufficient with specific mitigations in place. There are no scientific objections arising from this review to the authorisation for temporary supply for this product under Regulation 174.

Further information

The rest of this document, including sections on clinical aspects, user consultation, and the overall conclusion, can be found in the PDF.

Sours: https://www.gov.uk/government/publications/regulatory-approval-of-pfizer-biontech-vaccine-for-covid-19/summary-public-assessment-report-for-pfizerbiontech-covid-19-vaccine
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Obituaries

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Connie M. Ament, 62
Connie M. Ament, 62, of Conestoga passed away unexpectedly Sunday, October 10, 2021. Born in Lancaster, she was the daughter of the late Harold and Dorothy (McCallister) Hoak. She was the loving wife of Glenn Ament with whom she celebrated over 39 years of marriage.
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Luis Manuel Anavitate-Santos, 66
Luis Manuel Anavitate-Santos, 66, of Lancaster, went into the arms of the Lord October 4, 2021, surrounded by his loving family. Born in Ponce, Puerto Rico on October 29, 1954, he was the son of the late Jesus Manuel Anavitate-Colon and Fernanda Santos-Vargas. In June, he celebrated 45 beautiful years of marriage with Maria Anavitate-Pacheco.
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James Paul Antes, 62
James Paul Antes, 62, of Manheim, passed away on Friday, October 8, 2021 at home surrounded by his loving family. Born in Lancaster, PA he was the son of the late Doris (West) and Robert Antes. He was the loving husband to Dawn (Eberly) Antes.
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Anna Louise Kennamer Barnett, 83
Anna Louise Kennamer Barnett passed away Friday, September 24, 2021. She was born in Miami, Florida on January 31, 1938. Her parents were David W. Kennamer and Anna Louise Kennamer (Appelget).
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Barbara A. Bartolema, 60
Barbara A. Bartolema, 60, of Lititz, passed away at her residence on Tuesday, September 28, 2021.
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Linda J. Benfer, 81
Linda J. Benfer, 81, of Lancaster and formerly of Lebanon, passed away at her residence on Thursday, September 23, 2021, surrounded by her family.
She was the wife of Marvin R. Benfer, with whom she shared 64 years of marriage this past July 7th. Born in Lebanon, she was the daughter of the late John and Jean Auchenbach Falk.
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Irene R. Bernas, 95
Irene R. Bernas, 95, went home to be with the Lord on Saturday, October 2, 2021 after a short stay at Lancaster General Hospital’s Comfort Care Unit. Mrs. Bernas lived independently at Brethren Village in Lititz, PA. She formerly lived in Mt. Carmel, PA, where she was born and raised her family, for 78 years.
She was the wife of Leonard Bernas with whom she celebrated 60 years of marriage before his death in 2003.
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Matt Blasick, 53
After an 18-month fight with AML Leukemia, Matt Blasick passed away at home in Lancaster, Pennsylvania, on Oct. 11, with his beloved wife Melissa by his side. He was 53.
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Anne C. “Nancy” Blom, 97
Anne C. “Nancy” Blom, 97, of Lancaster and Ocean City, NJ, peacefully passed away from natural causes on October 3, 2021, surrounded by her loving family. Born on May 17, 1924 in Lansing, MI, she was the daughter of the late Royden and Anna (Gegg) Catanach. She was the devoted wife of Gerard “Gerry” Blom until his passing in 1979.
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Terry Lee “Mousey” Brown, 64
Terry Lee “Mousey” Brown, 64, of Lancaster, passed away at home on Saturday, October 9, 2021. Born in Lancaster, PA he was the son of the late Mary Frances Brown and Henry McKinley Rogers.
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Sandra J. “Sandi” Bruce, 66
Sandra J. “Sandi” Bruce, 66, of Gordonville, PA, formerly of Lancaster, PA and Mount Holly, NJ, passed away on Friday, October 15, 2021 at Lancaster General Hospital. Sandra was born in Lancaster and was the daughter of Dorothy (Steinman) Dolinger, of Columbia, PA and the late Kenneth LeRoy Sipe.
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Shirley M. Cates, 88
Shirley M. Cates, 88, of Salunga, passed away on Sunday, October 17, 2021, at Lancaster General Hospital. Born in Altoona, PA she was the daughter of the late Gilbert A. and Ada E. (Norris) Pringle. Shirley was the loving wife of the late Theodore “Ted” King who passed in 1978, the late Paul S. Rebman who passed in 2002, and the late Robert Cates who passed in 2009.
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Theresa V. (Bollotta) Cimmino, 91
Theresa V. (Bollotta) Cimmino, 91, of Lancaster, passed away on Sunday, October 17, 2021 at Hospice and Community Care. Born in Belleville, NJ she was the daughter of the late Mary (Massaro) and George Bollotta. She was the loving wife to the late Giro E. Cimmino.
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Donna M. Consylman, 76
Donna M. Consylman, 76, formerly of Lancaster, passed away on Tuesday, October 5, 2021, at UPMC Harrisburg. Born in Lancaster, she was the daughter of the late Charles H. Shaeffer and Bertha (Anstead) Shaeffer.
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Frank N. Corbin, Jr., 84
Frank N. Corbin, Jr., 84, of Lancaster, passed away at Brethren Village on Sunday, October 17, 2021. He was the loving husband of Brenda L. (Brinser) Corbin for 23 years. Frank’s first wife, Nicole (Sayers) Corbin died in 1988.
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Carol Davis, 70
Carol Davis, 70, of Landisville, passed away at Hospice and Community Care of Wednesday, October 13, 2021. Born in Lancaster, PA she was the daughter of the late Kathryn (Rudy) Henry and John Yellets, Sr.
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David M. DiCola, 67
David M. DiCola, 67, of Lancaster, PA passed away Sunday, October 10, 2021. He was the son of the late Albert and Nancy Gable DiCola.
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Donald Erb, 82
Donald W. Erb peacefully passed away and his soul left this earth on October 13 in his home after several days of visits from family and friends. That was his wish. Don amazed everyone by fighting cancer for more than three years.
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Christine M. Eshelman, 69
Christine M. Eshelman , 69, of East Petersburg, passed away Saturday, September 25, 2021, following a courageous battle against ovarian cancer. Born in Hazleton, she was the daughter of the late John B. and Margaret C. (Vacula) Oleksa. Christine was the loving wife of Vincent R. Eshelman, II, with whom she celebrated 30 years of marriage.
Christine M. Eshelman
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Daniel P. Etnyre, 83
Daniel P. Etnyre, 83, of Lancaster, passed away on Sunday, September 26, 2021.
Daniel P. Etnyre
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Ronald R. Evans, Jr., 63
Ronald R. Evans, Jr., 63, passed Wednesday, September 29, 2021, and Ronald R. Evans, Sr., 87, passed Thursday, September 30, 2021 both of Millersville, PA. Ronald, Jr.
Ronald R. Evans, Jr.
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Ronald R. Evans, Sr., 87
Ronald R. Evans, Jr., 63, passed Wednesday, September 29, 2021, and Ronald R. Evans, Sr., 87, passed Thursday, September 30, 2021 both of Millersville, PA.
Ronald R. Evans, Sr.
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Gloria Ann Free, 87
Gloria Ann Free, 87, a resident at Pleasant View Communities, passed away in the early hours on Wednesday, September 22, 2021. Gloria was married to Jerome, Jerry, Free for 64 years. Jerry passed away in September 2019. Gloria was the daughter of the late Lorenzo and Filomena Brignola. She lived her whole life in Lancaster, PA.
Gloria Ann Free
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Giuseppe Gambino, 46
Giuseppe Gambino, 46, of Manheim, passed away unexpectedly on Tuesday, October 12, 2021. Born in Carini, Sicily, he was the son of Carlo and Marianna (Conigliaro) Gambino. Giuseppe was the husband of Nicole (Marino) Gambino, who was the love of his life, and they would have celebrated 12 years of marriage this coming December. He was a loving father to their children, Mia and Luca Gambino.
Giuseppe Gambino
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Matthew R. Garman, 39
Matthew R. Garman, 39, of Lancaster, passed away on Thursday, September 30, 2021.
He was the husband of Kylee A. Kostenbader Garman, with whom he shared 3 years of marriage this past September 29th. Born in Lancaster, he was the son of Timothy L. Garman of Leola and Ann Schober Garman of Lititz.
Matthew R. Garman
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Carol M. Garrett, 68
Carol M. Garrett, 68, of Millersville, lost her battle with cancer on Monday, October 11, 2021, when she passed at home surrounded by her loving family. Born in Lancaster, she was the daughter of Marie (Fetter) Kopf and the late Albert “Albie” Kopf. Carol was the beloved wife of William L. Garrett, and they would have celebrated 42 years of marriage on October 19th.
Carol M. Garrett
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Alan Monk Geiger, 42
Alan Monk Geiger, 42, of Willow Street, passed away Friday, October 15, 2021 at home following a courageous battle against cancer. Born in Lancaster, he was the son of Joseph A. and Jacqueline (Monk) Geiger, Sr., of Berlin, MD. Alan was the loving husband of Vanessa (Alleman) Geiger, with whom he celebrated 17 years of marriage on October 5.
Alan Monk Geiger
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Sandra M. “Sandy” Greathouse, 83
Sandra M. “Sandy” Greathouse, 83, of Millersville, formerly of School Lane Hills, Lancaster, passed away on October 3, 2021, at LGH surrounded by her family. She was born in Hondo, Texas, and was the daughter of the late Dr. John H. and Frances E. (Haegelin) Meyer. Sandy is survived by her husband of 65 years, Ronald H. Greathouse.
Sandra M. “Sandy” Greathouse
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Theresa A. Greatti, 88
Theresa A. Greatti, 88 of Lancaster, passed away peacefully on Tuesday, October 12, 2021. Born in Trenton, NJ, she was the daughter of the late Carmine and Antimina Migliaccio, and the beloved wife to Richard V. Greatti for more than 64 years.
Theresa A. Greatti
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Rebecca Hope Gruver, 45
Rebecca Hope Gruver, 45, of Lancaster, passed away on Thursday, October 14, 2021, after a brief, yet courageous battle with sarcoma. Born in Long Beach, CA, she was the daughter of Raymond Cornelius the late Renate A. (Steinmetz) Cornelius. She spent over 26 years and created a beautiful family with Matthew Gruver.
Rebecca Hope Gruver
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Ashlee’ J. Harrison, 27
Ashlee’ J. Harrison, 27, of Willow Street, passed away quite unexpectedly on Wednesday, September 29, 2021. Born in Westwood, NJ, she was the daughter of Edward R. Harrison, Jr. and Rhonda Y. (Allen) Harrison, with whom she resided.
Ashlee’ J. Harrison
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Ruth A. Heidecker, 87
Ruth A. Heidecker, 87, of Willow Street passed away on Friday, September 24, 2021.
Ruth A. Heidecker
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James C. Hensel, 74
James C. Hensel, 74, of Lititz, passed away after a long illness at Hospice & Community Care, Mount Joy surrounded by family on October 1, 2021. Born in Lancaster to the late Victor and Betty Hensel, Lititz. He was the beloved husband of Elaine (Carson) Hensel. They were married on May 4, 1974.
James C. Hensel
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Deborah “Debbie” S. Herr, 64
Deborah “Debbie” S. Herr, 64, of Lititz, passed away at her happy place in Ocean City, MD on October 16, 2021. Born in Columbia, PA she was the daughter of William Splain and the late Doris (Frane) Splain. She was the loving wife of Michael L. Herr for over 43 years.
Deborah “Debbie” S. Herr
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Josephine A. “Jo” Hiemenz, 81
Josephine A. “Jo” Hiemenz, 81 of Lancaster, passed away peacefully on September 21, 2021 at Hospice and Community Care of Mount Joy. She was the daughter of the late Victor and Regina (Anthony) Mehaffey, and the beloved wife to her late husband John H. “Jack” Hiemenz III who passed in 2014.
Josephine A. “Jo” Hiemenz
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William J. “BJ” Holden, Jr., 46
William J. Holden, Jr., known to family and friends as “BJ”, 46, of Mountville, passed away at home on Saturday, October 2, 2021. Born in West Palm Beach, FL, he was the son of the late William J. Holden, Sr. and Betty (Myers) Holden. Newly wed on June 4, 2021, BJ was the beloved husband of Sheila (Hernandez) Nunez, and the loving father of his son, Aidian Holden.
William J. “BJ” Holden, Jr.
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Kathy M. Holliday, 71
Kathy M. Holliday, 71 of Lancaster, passed away at home with family by her side on Tuesday, October 12, 2021. She was the loving wife to Steven J. Holliday for over 38 years.
Born in West Chester, PA, Kathy was a graduate of Henderson High School.
Kathy M. Holliday
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Linda K. Howard, 76
Linda K. (Doull) Howard, 76, lived a great life that came to its end on Tuesday, October 5 as her body passed away after a short illness.
Linda K. Howard
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John B. Hoyt, 88
John B. Hoyt, 88, passed away peacefully Tuesday, October 5, 2021 at his Manheim Township home. He was born in Highland, IL on March 26, 1933 to the late Wilbur and Rose Marie (Frey) Hoyt. He was the 11th generation of Hoyt’s in America growing up on the family farm.
John B. Hoyt
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Barbara “Barb” Ann Kent, 82
Barbara “Barb” Ann Kent, 82 of Lititz, passed away at her residence with family by her side on October 4, 2021. Born in Ashland, PA she was the daughter of the late William and Alwyn (Noll) Hughes. She was also the beloved wife to Grant Kent, Jr. for over 62 years, and had shared her life with him for over 70 years.
Barbara “Barb” Ann Kent
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Richard L. Kephart, 93
Richard L. Kephart of Lititz passed away peacefully on October 4, 2021 at the age of 93. Born in Osceola Mills, PA on September 3, 1928 he was the son of the late Howard and Florence Kephart. He and his wife Marie (Shirk) Kephart celebrated their 60th wedding anniversary on June 24, 2021.
Richard L. Kephart
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Edward W. “Ed” Krasnai, Jr., 73
Edward W. “Ed” Krasnai, Jr., 73, of Mount Joy, formerly of Bethlehem, PA passed away due to complications from Covid on Monday, September 27, 2021 surrounded by his loving family.
Edward W. “Ed” Krasnai, Jr.
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Anne Marie Kroznuski, 74
Anne Marie Kroznuski, 74, of Lancaster, PA died October 5, 2021.
Anne Marie Kroznuski
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Carlene Landis, 72
Carlene Landis passed into her loving Savior’s arms on Wednesday, October 6th, 2021. Her family and friends were blessed to have Carlene's love and support for 72 years. Although heartbroken, her family rejoices in knowing she is at peace in her heavenly home.
Carlene Landis
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Barbara Ann Lauer, 75
Barbara Ann Lauer
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Walter Leach, Jr., 93
Walter “Skip” Leach, Jr., 93, formerly of Parkland / Langhorne, passed away at Ephrata Manor on Wednesday, October 6, 2021. He was born in Newtown to the late Walter Leach, Sr. and Gladys (Atkinson) Leach.
Walter Leach, Jr.
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Charles D. “Chuck” Leensvaart, 75
Charles D. “Chuck” Leensvaart, 75, of Lititz, passed away on Friday, October 15, 2021, at Landis Homes Retirement Community. Born in Chicago, IL he was the son of the late Barteld and Janet (nee Dykstra) Leensvaart. Charles was the loving husband of the late Beth Ann (Brink) Leensvaart with whom he shared 49 years of marriage.
Charles D. “Chuck” Leensvaart
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William E. “Billy” Lengel, 70
William E. “Billy” Lengel, 70 of Lancaster, passed away at home on September 23, 2021. He was the son of the late William C. and Patricia A. (Essick) Lengel.
William E. “Billy” Lengel
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Julia N. (Naumowich) Lewicki, 101
Julia N. (Naumowich) Lewicki, age101, of Lititz, PA passed away peacefully surrounded by family, nurses and friends at Moravian Manor on Friday, October 8, 2021. Born in Coatesville, PA she was the daughter of the late Sophie (Layuk) and Joseph P. Naumowich. She was the beloved wife to the late Walter J. Lewicki, Sr. who passed in 2007. She was just 3 months shy of her 102nd birthday.
Julia N. (Naumowich) Lewicki
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Nathan C. Longenecker, 19
Nathan C. Longenecker, age 19, passed away on Friday evening, October 8, 2021, at home with his family around him. He was under the care of hospice following a courageous eight-month journey with brain cancer. He was the son of Lynn and Laurie (Eshleman) Longenecker, brother of Maria Longenecker and Jesse Longenecker, Lancaster, PA.
Nathan C. Longenecker
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David J. Mack, 71
David J. Mack, 71, of Lancaster, PA, passed away on October 2, 2021.
David J. Mack
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Sandra Lee Martin, 78
Sandra L. Martin, 78, of Lancaster, passed away peacefully on Sunday, September 26, 2021, surrounded by family and friends at Maple Farm Nursing Center in Akron. Born in Coatesville, PA, she was the daughter of the late Thomas and Elaine (Brown) Rominger. Sandy was the wife of the late John H. Martin, and they were married for 48 years at the time of his passing in 2016.
Sandra Lee Martin
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James “Jim” R. Matthews, Jr., 74
James “Jim” R. Matthews, Jr., 74, of Millersville, PA passed away peacefully on Saturday, September 25, 2021 surrounded by his loving family. Born in Lancaster, PA he was the son of the late Evelyn (Stauffer) and James R. Matthews, Sr. He was the loving husband to Diane (Snyder) Matthews for almost 56 years.
James “Jim” R. Matthews, Jr.
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Dr. Edward V. McAssey, Jr., 86
Dr. Edward V. McAssey Jr., 86, of Lancaster, passed away peacefully on Saturday, October 16, 2021 surrounded by his family. Edward was the husband of Anne Buckley McAssey with whom he shared 63 years of marriage. Born in Queens, NY he was the son of the late Edward V. Sr., and Anne Marie Terzien McAssey.
Dr. Edward V. McAssey, Jr.
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William J. McCann, Jr., 84
William J. McCann, Jr., of Lancaster, PA, passed away at age 84 on October 15, 2021. Born in Philadelphia, he was the son of the late William J. Sr. and Kathryn McGuigan McCann.
William J. McCann, Jr.
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Michael P. McMahon, 47
Michael P. McMahon, 47, passed away surrounded by his family on Friday, October 1,2021.
Born in Darby, PA, he was the son of Michael P. and Joanne Nenstiel McMahon of Lancaster.
Michael P. McMahon
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Eddie “Munsta” Metzger, 32
Eddie “Munsta” Metzger, 32, of Millersville, tragically died in a motorcycle accident on Saturday, October 16, 2021. He was born in Lancaster and graduated from Solanco High School in 2009.
Eddie “Munsta” Metzger
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Leon Michael, Jr., 77
Leon Michael, Jr., 77, of Millersville, passed away on October 15, 2021 at Lancaster Nursing and Rehab following a long illness. He was the husband of Pamela Michael with whom he celebrated 30 years of marriage this past May 25th.
Leon Michael, Jr.
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Alex Gene Miller, 29
Alex Gene Miller, 29, of Columbia, passed away on Monday, October 4, 2021, at the Lancaster General Hospital. Born in Lancaster, he was the son of Leroy G. Miller of Columbia and Wanda C. Miller of Willow Street.
Alex Gene Miller
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Steven P. Morrison, 64
Steven P. Morrison, 64, of Mountville, passed away on Sunday, September 26, 2021 at UPMC Harrisburg, surrounded by family after a hard-fought 14 ½ year battle with Granulomatosis with Polyangiitis (GPA, formerly known as Wegeners).
Steven P. Morrison
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Mary E. Nieczyporuk, 82
MARY ELIZABETH (VERES) NIECZYPORUK, 82, absent from the body, and present with the Lord, October 4, 2021.
Mary E. Nieczyporuk
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Faith Nissley, 90
Faith G. (Eshleman) Nissley entered into rest at Hospice and Community Care on Friday, October 15, 2021. She was the daughter of John F. and Hattie (Graver) Eshleman born in Conestoga on October 26, 1930. She graduated from Penn Manor High School in 1948.
Faith Nissley
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John Alan O’Brien, 88
John Alan O’Brien, 88, a resident of Willow Valley Communities, passed away peacefully on Saturday, September 25, 2021. Born in Seroe Colorado, Aruba, where he lived until his teenage years, he was the son of the late Paul A. and Louise Conlon O’Brien. John was the beloved husband of Angela Rivera O’Brien, they celebrated 62 years of marriage in June of this year.
John Alan O’Brien
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Douglas K. Olsen, 59
Douglas K. Olsen, 59, of Lititz, passed away at Hospice & Community Care on Monday, September 27, 2021. He was born in Abington, PA to the late Kenneth L. and Helen (Willig) Olsen.
Douglas K. Olsen
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Francisco Geraldo Ortiz, Jr., 23
Francisco Geraldo Ortiz, Jr., 23, of Lancaster, passed away unexpectedly on October 13, 2021. Born in Manhattan, NY, he was the son of Francisco Geraldo Ortiz, Sr. and Silvia B. Agramonte.
Francisco Geraldo Ortiz, Jr.
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Allen “Andy” A. Perez, 47
Allen “Andy” A. Perez, 47, of Lancaster, PA passed away on Saturday, October 2, 2021 at Lancaster General Hospital surrounded by his loving family. Born in Lancaster, PA he was the son of Julio Alberto Perez, Sr. and Lorraine (Drake) Florian.
Allen “Andy” A. Perez
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Andrew L. “Drew” Perry, 40
Andrew L. “Drew” Perry, 40, of Landisville, passed away after a brief illness on September 24, 2021. Born in Baltimore, MD he was the son of Denise and James Maloney of Florida and the late James Perry.
Andrew L. “Drew” Perry
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William M. “Bill” Quinn, 93
William M. “Bill” Quinn, 93, of Lancaster, passed away peacefully at Landis Homes on Saturday, October 16, 2021, surrounded by his family. He was the loving husband of Victoria “Vicky” (Navari) Quinn with whom he shared 57 years of marriage.
William M. “Bill” Quinn
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Helen B. Retallack, 92
Helen B. Retallack, 92, passed away Saturday, October 16, 2021 at her Strasburg home. She was the wife of the late Kenneth L. “Red” Retallack, with whom Helen enjoyed 43 years of marriage before his death in 1998.
Helen B. Retallack
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Donna D. Rhoat, 73
Donna D. Rhoat, 73, of Lititz, passed away on Sunday, October 3, 2021, at WellSpan Ephrata Hospital. Born in Lancaster, she was the daughter of the late Joseph Dieterle and the late Theresa Moffett. Donna was the loving wife of Richard P. Rhoat, and they celebrated 20 years of marriage.
Donna D. Rhoat
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Cheryl D. Richwine, 78
Cheryl D. (Willis) Richwine, 78, passed away on October 6, 2021 at Moravian Manor. She was born in East Petersburg, Pa on August 10, 1943, the daughter of the late Joseph Sr. and Esther (Kiehl) Willis. She was the beloved wife of the late Harry R. Richwine Jr. who passed in 2018.
Cheryl D. Richwine
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Isabel Rodriguez Santiago, 81
Isabel Rodriguez Santiago, 81, of Lancaster, went into the arms of the Lord, September 28, 2021, surrounded by her loving family. Born in Patillas, Puerto Rico, she was the daughter of the late Alberto Rodriguez and Dorotea Diaz. She was the devoted wife of Jose A. Santiago for over 41 years, until his passing in November 2015.
Isabel Rodriguez Santiago
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John J. Rosales, 39
John J. Rosales, 39, of Douglassville and formerly of Lancaster, passed away at Pottstown Hospital on October 4, 2021. He was born in Palmira Cali, Colombia, South America to Maria P. Rosales of Lancaster and the late Jose Rosales, and he immigrated to the United States at age 13 in 1995.
John J. Rosales
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Michael “Easy” Andrew Rowe, 57
Michael “Easy” Andrew Rowe, 57 of York, passed away peacefully on Thursday, October 14, 2021. He was the son of Mary K. (Huss) Rowe and the late William Rowe.
Born and raised in Lancaster, Michael was a Penn Manor graduate.
Michael “Easy” Andrew Rowe
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Bruce (Cisco) Royall, 66
Bruce (Cisco) Royall, 66 Lancaster, PA. Was called home to eternal rest on 10/11/21 at his home. He was born in Philadelphia, PA.
Bruce (Cisco) Royall
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Teresa Spadea Ruhl, 79
Teresa Spadea Ruhl, affectionately known as “Momma Teresa and Aunt Teresa” passed away peacefully October 9, 2021 with her loving family by her side. She was the daughter of the late John L. Spadea Sr. and the late Helen LaMonica Wynn. She married Richard K. Ruhl Sr, who preceded her in death on November 13, 2015 and whom she met at Rocky Springs Amusement Park’s roller-skating rink during her junior year at Lancaster Catholic High School.
Teresa Spadea Ruhl
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Stephan M. Schalow, 64
Stephan M. Schalow, 64, of Lancaster, passed away on October 14, 2021. Born in Marshfield, WI, he was the son of Richard and Josie (Leatherman) Schalow.
Stephan M. Schalow
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Margaret Zeigler Schopf, 89
Margaret Zeigler Schopf of Lancaster passed on Monday, the 4th of October, 2021. Born October 7th, 1931 to Eugene and Margaret Ziegler and survived by her sister, Kathy.
Margaret was mother to Steve, Lisa, Eric, Marty and Stuart. Grandmother to Emily & Andrew Cooper & Grant, Kirstin & Lance.
Margaret Zeigler Schopf
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Sharon E. Settle, 62
Sharon E. Settle, 62, of Leola, went into the arms of the Lord surrounded by her children on Sunday, October 3, 2021. Born in Lancaster, she was the daughter of Edna (Stoltzfus) Lewis and the late Alvin L. Blank Sr., who unfortunately passed just nine days before Sharon.
Sharon E. Settle
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Shane Allen “Zippoboy” Shank, 40
Shane Allen Shank, 40, of Ephrata, peacefully embarked upon yet another journey on September 24th from complications of a traumatic brain injury due to an assault nearly two years ago. Shane was the beloved son of Mary Snyder Linger of Ephrata, loving stepson of George G. Ries of Lancaster, and son of Russell G. Shank of Elizabethtown. Shane leaves behind his sister, Amanda Ries of Ephrata, and two brothers, David Harnly and Michael Shank, both of Elizabethtown.
Shane Allen “Zippoboy” Shank
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Robert “Bob” E. Shreiner, 84
Robert “Bob” E. Shreiner, 84, of Lititz, passed away on Friday, September 24, 2021 at Hospice and Community Care. Born in Lititz, PA he was the son of the late Louella (Mellinger) and Victor Shreiner. He was the loving husband to Julia (Miller) Shreiner for almost 67 years.
Robert “Bob” E. Shreiner
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Jacqueline Sierra, 52
Jacqueline Sierra, 52, of Wrightsville PA, passed away Friday, October 1, 2021.
Jacqueline Sierra
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Michael L. Smith, 56
Michael L. Smith, 56 of Lancaster, passed away unexpectedly on Saturday, October 9, 2021. He was the son of the late Paul R. and Regina E. Smith, and the loving husband to Cindi Smith for over 21 years.
Michael L. Smith
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William R. Steinbaecher, 78
William R. Steinbaecher “Steiny” ,78, passed away Wednesday, October 6, 2021, due to Diabetic complications
William R. Steinbaecher
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Luther “Luke” M. Styer, 81
Luther M. Styer, 81, of Lititz, passed away on Wednesday, October 13, 2021 at his home surrounded by his family. Born in Rothsville, he was the son of the late John A. and Alverta (Rettew) Styer. Luke was the beloved husband of Lynne L. (Mathers) Styer for 60 years. Luke graduated from Warwick High School. He was a retired service technician for UGI for 35 years. He then worked at Haller for 15 years.
Luther “Luke” M. Styer
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Robert “Robbie” L. Thomas, 61
Robert “Robbie” L. Thomas, 61, of Lancaster, passed away on Saturday, September 25, 2021. Born in Lancaster, PA he was the son of the late Joe Grizzle and Olive Thomas.
Robert “Robbie” L. Thomas
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Caryl C. Trachte, 87
Caryl C. Trachte passed away on Monday, October 4, 2021. Caryl was born in Chicago, Illinois, December 28, 1933, the daughter of the late William and Ella Huster Coninx and grew up in Skokie, Illinois. She happily shared 65 years of marriage with her husband Byron.
Caryl C. Trachte
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Kay Dill Vollmar, 81
Kay Dill Vollmar, 81, of Willow Valley near Lancaster, Pa, formerly of Landenberg Pa. and Laurel, Md., died October 11.
Kay Dill Vollmar
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Barbara K. Walsh
Barbara K. Walsh, 91, of Mennonite Homes, passed away, Tuesday, October 5, 2021. Born in Lancaster, she was the daughter of the late Raymond and Bertha (Weber) Henderson. She was the wife of the late Leo M. Walsh.
Barbara K. Walsh
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Laura Romaine Wetzel, 83
Laura Romaine Wetzel, 83, editor of cookbooks, passed away on Saturday, October 2, 2021. Born in Ephrata, she was the daughter of the late Clarence Rhodes and Margaret Ream Rhodes Rathkey. Romaine was the wife of the late Marvin E. Wetzel for over 59 years, until his passing 2013.
Laura Romaine Wetzel
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Martin “Marty” Richard White, 85
Martin “Marty” Richard White, 85 of Lititz, passed away on October 1, 2021 with his loving family by his side. He was the son of the late Elwood and Eva (Stout) White, and the beloved husband to Bernice (Bleecher) White for over 63 years.
Martin “Marty” Richard White
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Martin R. White, 85
Martin “Marty” Richard White, 85 of Lititz, passed away on October 1, 2021 with his loving family by his side. He was the son of the late Elwood and Eva (Stout) White, and the beloved husband to Bernice (Bleecher) White for over 63 years.
Martin R. White
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Stephen T. Wickers, 69
Stephen T. Wickers, 69, of Mount Joy, passed away Sunday, October 10, 2021 at LGH. Born in Floral Park, NY he was the son of the late Thomas and Roberta (Munda) Wickers. He was the loving husband of Janet (Stoye) Wickers with whom he shared over 42 years of marriage.
Stephen T. Wickers
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David Clyde Williams, 75
David Clyde Williams, 75 of Lancaster, passed away at Lancaster General Hospital on Friday, September 24, 2021. He was born in Fayetteville, NC to the late Rev. C. T and Nellie Ruth (Hammond) Williams.
David Clyde Williams
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J. Clair “Wit” Witwer, 67
Jay Clair Witwer, 67, of Millersville, passed away at home, Tuesday, October 12, 2021. Born in Lancaster County, Clair was the son of the late Roy V. and Emma (Hoover) Witwer. He was the loving husband of Jane M. (Johnson) Witwer, with whom he celebrated 35 years of marriage.
J. Clair “Wit” Witwer
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Anthony J. Zigment, 96
Anthony J. Zigment, 96, of United Zion Retirement Community, Lititz, formerly of Manheim Township, passed away on Friday, October 15, 2021. He was born in Scranton, PA and was the son of the late Anthony J. and Julia M. (Powell) Zigment. He was preceded in death by his wife Shirley Welsh Musser Zigment in 2006. He was also previously married to Marcella Kozloski.
Anthony J. Zigment
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S. Richard (Dick) Zook, 88
S. Richard (Dick) Zook of Lititz, previously of East Petersburg passed away on October 11, 2021. He passed away after a breakthrough case of Covid-19 with underlying conditions. He was a resident of Moravian Manor with a diagnosis of Alzheimer’s.
S. Richard (Dick) Zook
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Sours: https://www.snyderfuneralhome.com/obituaries/

UK Covid daily cases soar past 52,000 as Tories resist calls for Plan B rules

A further 52,009 new coronavirus cases were recorded in the UK in the past 24 hours as the Government continues to resist calls to trigger Covid winter contingency plans.

Meanwhile, 115 further deaths were recorded in the past 24 hours.

It comes after 179 deaths were recorded on Wednesday.

Today's rise in cases is the second time more than 50,000 new Covid infections have been recorded in a 24 hour period this week.

According to the Government's coronavirus dashboard, 54,571 infections were recorded on October 18 but it says the tallying is complete - meaning the true figure could be higher.

Covid cases have soared above 50,000 for the second time this week

The grim figures come just 24 hours after Health Secretary Sajid Javid resisted calls to implement the measures despite his warning that the number of cases could rise to 100,000 a day.

Mr Javid told a Downing Street press conference on Wednesday the Government was focusing on getting unvaccinated Brits to come forward for their jabs and rolling out booster shots.

Health Secretary Sajid Javid has warned the UK could see 100,000 new Covid cases a day

He claimed the NHS was facing a sustainable level of pressure as the winter approached and said further curbs would not be brought in at the moment.

However, he warned restrictions could be brought up before Christmas if people didn't get their booster jabs.

The Government has drawn up a list of "Plan B" contingency measures as part of efforts to fight Covid this winter, which includes a return to mandatory face masks, working from home and vaccine passports.

Mr Javid confirmed on Wednesday this was not going to be involved at this time.

Cabinet Office officials are said to be discussing proposals for a clampdown on socialising, which could form part of a “Plan C” if booster jabs don't bring the virus under control by Christmas.

Health Minister Edward Argar said it wasn't "being actively considered" but the Government would always look at ways to prevent the virus from spiralling out of control.

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It comes as doctors have accused ministers of being "wilfully negligent" by failing to implement Covid "Plan B", which would see the return of masks, working from home and use of vaccine passports.

Furthermore, alarming new figures show the number of Covid patients is rising in all English regions - with Birmingham, Manchester and Nottingham among the areas heaviest hit.

UK cases have spiralled in recent days, with more than 320,000 people testing positive for the virus in the past seven days - a 17 per cent rise from the previous week.

Those who have been called to get their booster jabs ahead of winter are being encouraged to do so

Fatalities are also on the rise, with 954 lives lost to Covid - more than 21 per cent higher than the week before.

More than 6,000 people were admitted to hospital in that time, a rise of more than 11 per cent.

Furthermore, data from the ZOE Covid study has also revealed that Covid cases have spiked 17 per cent in the last week with figures showing more than 23,000 new daily cases amongst the double vaccinated population.

There are currently 81,823 new daily symptomatic cases in the UK on average, based on PCR and lateral flow test data from up to five days ago, according to the figures.

This compares to 69,993 last week.

Data also shows that cases continue to rise amongst those double vaccinated and it’s estimated there are currently 23,199 new daily symptomatic cases, up from 18,817 last week.

The UK R value is estimated to be around 1.1 while regional R values are; England, 1.0, Wales, 1.0, Scotland, 1.1.

The study also finds 1 in 63 people in the UK currently have symptomatic Covid.

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Sours: https://www.mirror.co.uk/news/uk-news/breaking-uk-covid-cases-soar-25269718

Obituaries lnp

LNP (Lancaster, Pennsylvania) Newspaper Obituaries (2014 - Current)

Enter your ancestor's name below and we'll search obituaries to help you learn more.

Uncovering your family history can be difficult. LNP obits are an excellent source of information about those long-lost family members in Lancaster, Pennsylvania

With the LNP obituary archives being one of the leading sources for uncovering your history in Pennsylvania, it's important to know how to perform a LNP obituary search to access this wealth of research from newspapers all across the country.

Our online database enables you to perform searches without the hassle of performing manual searches through old records.

Some of the most beneficial reasons to look into LNP local obituaries include:

  • Uncover the branches of your family tree.
  • Connect with extended family members.
  • Discover the stories of your ancestors.

Explore the comprehensive records in our online database, and you'll gain access to almost 150 years of local history.

Plus, 95% of GenealogBank records cannot be found through any other online services.

How to Search LNP Obituary Archives

Looking up LNP obituaries in Pennsylvania doesn't have to be difficult. Whether you're trying to understand where you come from for the first time or you're looking to add some detail to a family tree, it couldn't be easier to perform a LNP obituary search.

All you have to do to get started is enter the last name of a chosen relative and press the “Search” button. It’s an excellent launching point for further research into those elusive relatives.

You can also get some additional guidance by downloading the free “Tips for Searching Titles” guide.

If you’re trying to get more information on a specific relative, follow these steps to perform an advanced search of the LNP obituary archives.

  • Step One – Begin by entering the first and last names of your relative. You’ll get more accurate results if you also have a middle name. Our search results will present you with close match obituaries.
  • Step Two – Add a keyword, such as a school or a town, to narrow your search results .
  • Step Three – Exclude keywords to avoid uncovering obituaries unrelated to your family tree.
  • Step Four -Include a year range. With almost 150 years of history, the chances are your ancestors share the same name as someone else’s ancestor.
  • Step Five - Get different results by changing the sorting options. You can order your results by showing the best matches, newest entries, and oldest entries.

Tips for a Successful LNP Obituary Search

Genealogy research can be challenging as many records are incomplete or filled with mistakes. For a successful LNP obituary search, it’s good to have multiple strategies at your disposal to ensure you get the correct relative.

Most older obituaries will include some pieces of family information. Obituaries can be used to uncover information about other relatives or to confirm that you have the right person in Lancaster, Pennsylvania.

For a successful search of LNP obituaries, follow these tips:

  • Use information from more recent ancestors to find older relatives.
  • Try searching by initials. Many old LNP obits used initials instead of full names.
  • Are you looking for a female relative? Try searching for their husband’s name.
  • Perform searches by using common misspellings. TITLE editors often didn’t fact-check spellings in the past.

By implementing these strategies, you can go deeper with your research and uncover the ancestors you never knew you had. It’s also ideal for fact-checking, as many obituaries weren’t necessarily created with 100% accuracy.

How to Find Pennsylvania Death Notices in the LNP

Finding death notices in the LNP can be another vital source of genealogical research. But what’s the difference between a death notice and an obituary?

Although some people use the terms interchangeably, they’re actually two different things. Obituaries describe the person, who they are, and what they did in their lives. Death notices, on the other hand, are formalized reports of someone’s death.

Family members would have published death notices in the LNP to detail the person’s name, age, residence, and any information about the funeral service. As family members typically wrote these, they tend to be relatively accurate.

Death notices can help extract more information about an ancestor and uncover where they happen to be buried. So, how do you look up local death notices and sift through hundreds of years’ worth of history? If you want to find death notices alongside LNP obits, follow these tips:

  • Include Boolean operators and proximity search techniques.
  • Use multiple collections to fact-check any found records.
  • Connect other family members mentioned in the death notice to confirm whole sections of your family tree.

The LNP records are invaluable sources of historical information about local people. We make it easy for you to search, discover, and share your family’s untold story.

Other Useful Collections To Try

Trace your family history with the GenealogyBank database to begin growing your family tree.

Do you want to learn even more about unlocking your history? Visit the GenealogyBank Learning Center for tips and inspiration.

Sours: https://www.genealogybank.com/explore/obituaries/all/usa/pennsylvania/lancaster/lnp

Queensland Treasurer Cameron Dick condemns NSW government's push to open up 'regardless of the health consequences'

Queensland's Treasurer Cameron Dick has hit out at the New South Wales government's management of its latest COVID-19 outbreak, saying the state was too slow to respond.

Speaking in state Parliament, Mr Dick criticised NSW Premier Gladys Berejiklian and her government's response to the Delta outbreak.

Queensland COVID-19 snapshot

In the past 24 hours:

  • Locally acquired cases: 1
  • Other sources: 4
  • Tests: 7,616

Queensland's vaccine roll-out (percentage of those aged 16+):

  • First dose: 73.7 per cent
  • Second dose: 58.7 per cent
Latest information from Queensland Health.

"The people of NSW deserve all of our sympathy and support; however, the actions of their government must be questioned," he said.

"The NSW government did not go hard. The NSW government did not go fast.

"Now, as they drag down the national economy and the morale of their own people, all they talk about is opening up, regardless of the health consequences."

NSW recorded 1,164 new locally transmitted COVID-19 cases and three deaths in the latest reporting period, bringing to 96 the number of deaths connected to the current outbreak.

Catch up on the main COVID-19 news from October 21 with a look back at our blog

Ms Berejiklian said it was her "absolute goal" to have every Australian home for Christmas. 

"Once we hit 80 per cent double-dose vaccination, NSW will continue what we've done during the entire pandemic — do more than our fair share of reuniting families, of having a compassionate approach, accepting we're all Australians and that's our absolute goal," she said.

Gladys Berejiklian

Ms Berejiklian said she did not understand why some states and territories were walking away from the national plan to end lockdowns once 80 per cent of the Australian population had been double vaccinated.

Western Australia Premier Mark McGowan has recently said opening up to NSW at 70 per cent double dose would be akin to deliberately infecting his citizens, and freedoms would have to be wound back.

Queensland's Chief Health Officer Jeannette Young said the state would "probably" open its border at 80 per cent double doses, but she would reassess closer to the time.

Read more about the spread of COVID-19 in Australia:

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Play Video. Duration: 3 minutes 59 seconds

'They want us to run up the white flag'

Mr Dick said the Queensland economy has been performing strongly with employment up 95,000 for July compared with March 2020 and an overall unemployment rate of 5.2 per cent.

He said real retail trade in July was also up 11.5 per cent compared with the pre-COVID level.

Want more local news?

The Queenslander sign in the NSW-Queensland border town of Wallangarra in Queensland on October 8, 2020.

We offer tailored front pages for local audiences in each state and territory. Find out how to opt in for more Queensland news.

Read more

Mr Dick also blasted the federal government's handling of the vaccine rollout and international hotel quarantine.

"It is no accident that these LNP governments keep falling into these errors. That's because these LNP governments are chock full of crazies," he said.

"They don't believe in border controls. Some of them don't even believe in COVID.

"They want us to run up the white flag and open the borders to an uncontrolled outbreak in NSW just because they say they have hit their vaccination target."

Mr Dick later withdrew the word "crazies" at the request of Speaker Curtis Pitt, who said it was unparliamentary language that had implications about mental health.

A Prime Minister's Office spokesperson said Scott Morrison addressed the vaccine rollout in told federal Parliament on Monday. 

"It's all about how you finish the race, as I've said before in this place," Mr Morrison said.

"What has been achieved in these many months now, despite the setbacks that we had early on in the vaccination program … is that it has already been brought back to being able to vaccinate everybody before the end of the year."

Sewage testing to begin in border town

Queensland Health will start COVID-19 sewage testing in the border town of Goondiwindi.

Last month, the ABC revealed outback Queensland border towns were not being included in the state government's sewage testing for COVID-19 fragments – a key early warning sign to help prepare for outbreaks.

Tests were only being conducted as far west as Toowoomba, about 120 kilometres from Brisbane.

On Tuesday, a Queensland Health spokesperson confirmed it had now invited Goondiwindi to join the wastewater surveillance program.

However, the spokesperson did not say exactly when the testing would start other than it would be "in due course".

Queensland authorities are on high alert over the rapid spread of COVID-19 in western NSW, including into some local government areas on the Queensland border.

COVID fragments were detected in the NSW town of Moree, about 150km south of Goondiwindi.

NSW Health's COVID testing website lists positive tests done on August 24, but the website does not indicate if there had been more recent tests or results.

The Moree sewage treatment plant services about 10,000 people.

Further west, in the NSW settlement of Goodooga which is less than 20km from the Queensland border, six cases of COVID-19 have been reported.

Local authorities said the cases were all in the one family, which is isolating.

The tiny town is close to the Queensland town of Hebal, about 650km west of Brisbane.

Queensland Health also revealed it had not yet needed to manage any COVID-19 positive patients on behalf of NSW Health — so far.

"We remain ready and willing if NSW requests assistance," the spokesperson said.

Read more about the vaccine rollout:

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Sours: https://www.abc.net.au/news/2021-08-31/qld-coronavirus-treasurer-dick-hits-out-at-nsw-government/100422322

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Lancaster Homicide

Community content is available under CC-BY-SA unless otherwise noted. A killer who beat a woman to death because she was dressed as a Goth has failed to get his sentence reduced. LANCASTER - Two men were fatally shot Monday in the Lancaster and a person of interest was detained for questioning, authorities said. Leib began deliberating late this. County Fire personnel were initially called to the scene for a gas leak, but. com/Robert Maltby's interview w. David Meadows and Amy Manning are the parents of the victim. Lancaster County, PA — A man and woman from Lancaster County have been charged with homicide in connection with the death of a 4-month-old in May, according to police. Her death was ruled a homicide, police say. 1, at Americas Best Value Inn & Suites on the 44100 block of Sierra Highway. "That was … a day," he. One occurred in 1950. PARADISE, Pa. Murder mystery dinner theaters in Lancaster come in all sorts of different flavors. LANCASTER, N. An autopsy performed by the Lancaster County Coroner's Office determined Helen Miller, who suffered from cerebral palsy, had been stabbed several times. Van Evra, both 83, just before 1 a. Officers found Ruth A. 46% of those have been in hospital. Jun 21, 2016 · Homicide Victim: Charles Lancaster Tuesday, June 21, 2016 On Thursday, April 16, 2015 at approximately 2:47 pm, Mr. Sharpo! Mystery & Magic - Top Rated. The number of homicides stood at 7. Late Tuesday afternoon, the Chester County Sheriff's Office obtained murder warrants for George "Si" Linward Faile of Lancaster and Amber Nicole Harris of Chester. A 65-year-old woman found dead inside her Lancaster County home last week died of strangulation, the coroner has ruled, according to the LNP newspaper. , 32, was arrested Wednesday in connection with the stabbing death and dismemberment of his father, Donald Meshey Sr. Authorities state that when officers arrived at the scene, they discovered a male victim lying in the street. Murder of her sister. Lancaster died as a result of his injuries on April 17, 2016. County Fire personnel were initially called to the scene for a gas leak, but. RICHLAND TOWNSHIP — A Lancaster man has been charged with murder after a fatal shooting Monday night resulted in one death. Lancaster County, PA — A man and woman from Lancaster County have been charged with homicide in connection with the death of a 4-month-old in May, according to police. Warrants have been issued charging Clinton with attempted murder, failure to stop for blue lights, reckless driving and speeding. East Lampeter Township police and Pennsylvania Police charged Justo Smoker with criminal homicide. The Lancaster County District Attorney's Office announced this week that police are investigating the death of a 65-year-old New Holland woman earlier this month as a homicide. 120th Street West And Ave #H, Lancaster, CA 93536. in Lancaster County earlier this month. LANCASTER, Ohio — A man and three 16-year-old boys are now charged with murder in the fatal shooting of another 16-year-old during a robbery. RICHLAND TOWNSHIP — A Lancaster man has been charged with murder after a fatal shooting Monday night resulted in one death. Sep 07, 2021 · Man found shot and killed in Lancaster. Teacher's gruesome 1992 death launches decades-long mystery: 20/20 Oct. The Lancaster County Coroner confirms the 65-year-old woman found dead in her New Holland home last week was strangled. The then-20-year-old was murdered 10 years ago today in a tragic hate crime. Lancaster man indicted in connection with fatal Richland Township shooting. When a wealthy landowner's body goes missing on the night of his death, a sinister web of secrets and lies is exposed in the village of Little Malton. South Middle School special education teacher Eleanor Mends passed away after battling COVID-19, according to school officials. The Lancaster Police Department and BAIR Analytics Inc. (MORE: DNA on gum, water bottle leads to DJ's arrest 26 years. September 7, 2021 9:03 pm. LANCASTER — Los Angeles County Sheriff's Department Homicide detectives continued their investigation Monday morning into the circumstances surrounding the shooting death of man near downtown Lancaster. Get Alerts. , 67, by Lancaster police. - A Lancaster man is facing homicide and abuse of a corpse charges after a welfare check turned up a human head and body. — Officials say a second middle school teacher has died from COVID-19 complications in Lancaster County. Souffrant was injured in the incident and remained in the hospital until March 16. 120th Street West And Ave #H, Lancaster, CA 93536. Miss Lancaster's murder, which occurred on the same night that father-of-three Garry Newlove was being killed by a gang of drunken youths 40 miles away in Cheshire, yet again highlights the deadly. He is wanted for attempted murder, failure to stop for blue. For Lancaster, we found that the violent crime rate is one of the highest in the nation, across communities of all sizes (both large and small). By: Associated Press Posted on: Tuesday, October 23, 2012 < < Back to Authorities in central Ohio say three people, including an off-duty police. by Megan Arellano Before he was sentenced Friday to 49 years in prison, Grant Johnson spoke at length about how prosecutors vilified him. , 32, is charged with criminal homicide, abuse of a corpse and tampering with evidence. (The US average is 22. The Lancaster Police Department now has an online crime map called RAIDS Online that maps and analyzes crime data and alerts Lancaster citizens about crimes in their area. Take in the fun at a historic mansion, or solve the mystery over dinner on a moving train. 21, 2014, 10:25 p. A man was fatally shot Monday in the Lancaster area. 45, with multiple gunshot wounds to his upper body. Sep 07, 2021 · Man found shot and killed in Lancaster. According to. A charge has been filed in connection with a child's untimely death in Lancaster, South Carolina last month. Mom, daughter killed by husband in murder-suicide months after winning $2M lottery. share with. Sharpo! Mystery & Magic - Top Rated. Violent Crimes - Murder Rape Robbery Assault. LANCASTER, PA — The Lancaster Bureau of Police announced the arrest of Donald Meshey Jr. The Lancaster Police Department now has an online crime map called RAIDS Online that maps and analyzes crime data and alerts Lancaster citizens about crimes in their area. Lancaster, Nebraska News, News. , Jean Hargadon Wehner, a 16-year-old junior at the all-girls Catholic school, followed the priest to the parking lot and climbed into the passenger seat of his light blue. 36% decline from 2017. , Sunday on the 44200 block of Beech Avenue. " This language unequivocally expresses that Lancaster was charged with murder while engaged in the underlying crime of burglary. (WHTM) — Two Lancaster County adults are charged with criminal homicide after a four-month-old baby under their care drowned in a bathtub. Declan Lancaster had been charged with the murder of Patryk Mortimer but admitted manslaughter when he appeared at Newcastle Crown Court. Back to School. Homicide Victim: Charles Lancaster Tuesday, June 21, 2016 On Thursday, April 16, 2015 at approximately 2:47 pm, Mr. 11/04/1827. Edition of Lancaster New Era. Rowe Eventually Pleaded Guilty to Mirack's Murder. Do you have information to share about the life of Jonathan Luke Reyes? The Homicide Report needs your help. Now, a reexamination of the case by a hard-charging UVA lawyer has turned up troubling questions. The then-20-year-old was murdered 10 years ago today in a tragic hate crime. The shooting was reported about 10:10 a. (MORE: DNA on gum, water bottle leads to DJ's arrest 26 years. In the last 5 years Lancaster has seen. Stacy Fairchild Find-A-Grave: Stacy Fairchild Arrest Made In 1989 Slaying Evidence from DNA rekindled 1989 case Man charged in 1989 killing DNA provided break in 20-year-old killing Man Takes Plea Deal In Teen's 1989 Slaying Man gets 7 to 25 years for murder Man Sentenced In Teen's 1989 Slaying Movies/Documentaries On the Case with Paula…. LANCASTER — Los Angeles County Sheriff's Department Homicide detectives continued their investigation Monday morning into the circumstances surrounding the shooting death of man near downtown Lancaster. Yes, they absolutely have the killer's DNA in Erma Kaylor's brutal murder. With Johnny Cash, Andy Griffith, Earl Hindman, Ed Van Nuys. If you have a photo of a homicide victim to share, email it to [email protected] For Lancaster, we found that the violent crime rate is one of the highest in the nation, across communities of all sizes (both large and small). LANCASTER (CBSLA. An 18-year-old from Lititz has been charged with the death of the driver of a horse-and-buggy after he hit the vehicle and fled the scene, according to East Earl Township police. Donald Meshey Jr. Miss Lancaster's murder, which occurred on the same night that father-of-three Garry Newlove was being killed by a gang of drunken youths 40 miles away in Cheshire, yet again highlights the deadly. Half-brother charged in killing 47-year-old at family home on Saturday, Sept. Deputies were sent to 218 Railroad avenue just before 5AM that day and that's where they found Kenneth Morehead Jr. Rex Parris told the Los Angeles Times that both victims were decapitated, calling the incident "pretty brutal. 4 hours ago · A Lancaster man was charged with homicide on Wednesday after he showed police a human head and admitted to stabbing a “cadaver doll” at his Cabbage Hill residence, according to Lancaster police. Justo Smoker, 34, has been charged with criminal homicide in connection with the June 21 disappearance, the Lancaster County District Attorney's Office said. She died from her injuries in hospital 13 days later, aged 20 years old. The Lancaster Police Department is searching for 27-year-old Quinterius Lamont Clinton, of 1627 Kaywood Drive. Mary Magrath. Teen accused in York homicide is charged in deadly hit-and-run in Lancaster. LANCASTER, N. Authorities state that when officers arrived at the scene, they discovered a male victim lying in the street. 4) NOTE: Click on the links below to see charts for each crime category. He was subsequently transported…. Buck Ruxton (born Bukhtyar Chompa Rustomji Ratanji Hakim; 21 March 1899 - 12 May 1936) was an Indian-born British physician convicted and subsequently hanged for the September 1935 murders of his common-law wife, Isabella Ruxton (née Kerr), and the family housemaid, Mary Jane Rogerson, at his home in Lancaster, England. LANCASTER, S. The indictment plainly states that Lancaster was charged with killing Allison "while in the commission of the crime of burglary as set forth by section 97-17-33 of the Mississippi Code of 1972. Lancaster (KDKA) — A 32-year-old man from Lancaster has been arrested and charged with murder after police found a human head stored in a home freezer. Lancaster County District Attorney Craig Stedman announces charges in the 1992 cold case killing of Christy Mirack during a news conference at the Lancaster County Courthouse in Lancaster, Pa. Lancaster, CA 93535. 1,057 people in Lancaster County have died from COVID-19. Margaret Wishart. A statement from Lancaster County School. - Lot / Land for sale. David Meadows of Ronks was arrested Friday morning in West Earl Township by Pennsylvania State Police. If you look on yelp (searching" murder mystery train" within the Strasburg Railroad reviews) there are actually 3 positive reviews from 2018. Lancaster, CA 93535. Two Lancaster County adults are charged with criminal homicide after a four-month-old baby under their care drowned in a bathtub. Man fatally shot in Lancaster, homicide investigation underway. , 32, is charged with criminal homicide, abuse of a corpse and tampering with evidence. 17106 E Avenue K #8, Lancaster, CA 93535. Wednesday, Sept. courtesty of Greg Suskin, WSOC-TV. LANCASTER - A Lancaster County man pleaded guilty to third degree murder, kidnapping, and other charges in connection with the death of 18-year-old Linda Stoltzfoos. The murder mystery play was "The Choir Sang Murder!" by Act I Productions. A Lancaster County couple has been arrested and charged in connection with the homicide of a 4-month-old baby. , a 17-year-old standout senior wide receiver at Lancaster High School in Texas. Alec Devon Kreider (February 4, 1991 – January 20, 2017) was an American murderer, convicted of the killing of three members of the Haines family in Manheim Township, Pennsylvania, on 12 May 2007. LANCASTER — A Pennsylvania man faces homicide charges after a human head was found in a freezer at his family's home and a dismembered body was found in a bed. Linda Stoltzfoos -- 18 at the time she disappeared -- was last seen on June 21. Update 4/21/2021 at 4:30 p. Shooting 02/23/2021 1:50 PM 100 BLOCK OF WEST CHESTNUT STREET. LNP newspaper reports that a Lancaster County. The victim and her boyfriend Robert Maltby were attacked by a number of teenage boys w. 11/04/1827. A man was fatally shot Monday in the Lancaster area. According to Fairfield County Sheriff Alex Lape, deputies were. The coroner determined the manner of death. — Deputies in Lancaster County say a 21-year-old man wanted in connection with a deadly shooting just outside Kershaw in early August has turned himself in. LANCASTER, N. The Lancaster Police Department is searching for 27-year-old Quinterius Lamont Clinton, of 1627 Kaywood Drive. Murder of Jane Kelly (infant) 22/03/1828. The 2019 crime rate in Lancaster, CA is 360 (City-Data. , on the 44000 block of 15th Street West in Lancaster, according to investigators. Friday, January 17, 1975 AN. RICHLAND TOWNSHIP — A Lancaster man has been charged with murder after a fatal shooting Monday night resulted in one death. The Lancaster TX murder/homicide rate for 2016 was 10. Lancaster, PA - Amish Country in Pennsylvania. Local Lancaster Newspapers. 12/30/20 Update: Preliminary hearing for murder charge was postponed. Teen accused in York homicide is charged in deadly hit-and-run in Lancaster. The City of Lancaster and the City of Palmdale Host an In-Person Fireworks Event for Independence Day. Phillip Cornelius Sullivan, II struck a horse drawn buggy (su…. Michael Thomas, 62, was killed. Ten years on, have attitudes changed or are young people scared to be different? On the. 1 day ago · LANCASTER, S. Article continues below advertisement. Meadows was arrested on Friday in West Earl Township. , on the 44000 block of 15th Street West in Lancaster, according to investigators. Alec Devon Kreider (February 4, 1991 – January 20, 2017) was an American murderer, convicted of the killing of three members of the Haines family in Manheim Township, Pennsylvania, on 12 May 2007. Jonathan Luke Reyes, a 33-year-old Latino male, died Thursday, Aug. August 12, 2021, 9:05 AM. May 05, 2021 · Sophie Lancaster was murdered aged just 20. Three Dead In Overnight Lancaster Murder-Suicide. 36% decline from 2017. Credit: Lancaster County Sheriff's Office. Sophie Lancaster's mum, Sylvia, The murder charges against the other three - two 15-year-olds and a 17-year-old who were kept anonymous - were dropped. South Middle School special education teacher Eleanor Mends passed away after battling COVID-19, according to school officials. Crime Map for Lancaster, PA. Manly Maurice Thompson. Murder in Coweta County: Directed by Gary Nelson. LANCASTER, PA — Police in the City of Lancaster are conducting a homicide investigation after officers responded to the 500 block of Third Street for a report of a shooting. The suspect was wanted for murder in the shooting death of Kenneth Morehead Jr. Murder In Lancaster County The history and background of at least two local murders in Lancaster County, PA. — A man and woman from Lancaster County have been arrested and charged with homicide in connection to the drowning death of a four-month-old baby at a hotel on Lincoln Highway East. Violent Crimes - Murder Rape Robbery Assault. Lancaster is a city in the Antelope Valley and one of the 272 neighborhoods in Mapping L. Now we are expanding that goal to include a photograph for every victim. Donald Meshey Jr. While Police have released the suspect's name and photo, MyChesCo has chosen to not disclose the juvenile's identity due to the suspect's age. Save this home. com/Robert Maltby's interview w. 2 days ago · A 65-year-old woman found dead inside her Lancaster County home last week died of strangulation, the coroner has ruled, according to the LNP newspaper. The murder charges against the other three - two 15-year-olds and a 17-year-old who were kept anonymous - were dropped. Get the details. LANCASTER — Los Angeles County Sheriff's Department Homicide detectives continued their investigation Monday morning into the circumstances surrounding the shooting death of man near downtown Lancaster. In Lancaster you have a 1 in 37 chance of becoming a victim of crime. Los Angeles County Sheriff's Homicide detectives are responding to Lancaster Sheriff Station to investigate the death of a male adult. 4) NOTE: Click on the links below to see charts for each crime category. The murder suspect/suicide victim has been identified as 40-year-old Jeremy Whitman of Lancaster, according to the Los Angeles County Coroner's Office. Lancaster died after 13 days in a coma when her family agreed to turn off her life-support machine. A Lancaster man was charged with homicide on Wednesday after he showed police a human head and admitted to stabbing a "cadaver doll" at his Cabbage Hill residence, according to Lancaster police. com crime index), which is 1. Thursday, March 14, 1974 A-THURSDAY, MARCH 14, 1974 DEMANDED BY HEARST KIDNAPERS Judge Weighs SLA TV Appearance HILLSBOROUGH, Calif. Take in the fun at a historic mansion, or solve the mystery over dinner on a moving train. When they arrived, they found two male Hispanics in their 30s, suffering from gunshot wounds to their upper torsos. Christy Mirack. in Lancaster County, PA in June of 2022! We are currently taking bus tour and large group reservations. Lancaster County District Attorney Craig Stedman announces charges in the 1992 cold case killing of Christy Mirack during a news conference at the Lancaster County Courthouse in Lancaster, Pa. Sophie's mother would come into my high school to spread awareness regarding hate crimes and bullying of any kind. Lancaster homicide shooting investigation Video. , 32, is charged with criminal homicide, abuse of a corpse and tampering with evidence. A sign seeking information on the 1992 murder of Christy Mirack is seen in the Lancaster, Pa. The Homicide Report's goal is to tell the story of every victim. Declan Lancaster had been charged with the murder of Patryk Mortimer but admitted manslaughter when he appeared at Newcastle Crown Court. On Wednesday, September 1, 2021, at approximately 9:48 A. A man was fatally shot Monday in the Lancaster area. DJ is convicted of 1992 murder after DNA from water bottle and chewing gum led to arrest. Year over year crime in Lancaster has decreased by 19%. Sarah Jones. (FOX 46 CHARLOTTE) - The Lancaster Police Department is actively searching for an 'armed and dangerous' suspect Monday after an officer-involved shooting following a high-speed police chase. Jun 11, 2020 · KCAL 9 News at 4:00 08:59 - 2H AGO. Police say, David Meadows, 27, of Ronks, was arrested Friday morning in West Earl. County Fire personnel were initially called to the scene for a gas leak, but. While Police have released the suspect’s name and photo, MyChesCo has chosen to not disclose the juvenile’s identity due to the suspect’s age. According to. Arrest made in murder of Lancaster man. Two Lancaster County adults are charged with criminal homicide after a four-month-old baby under their care drowned in a bathtub. Three Dead In Overnight Lancaster Murder-Suicide. LANCASTER, Calif. The coroner determined the manner of death. Remains were found near Dutchland Inc in Lancaster County on Wednesday In December last year Justo Smoker, 34, was charged with criminal homicide Dutchland Inc is the former workplace of Smoker. com/Robert Maltby's interview w. Crime Map for Lancaster, PA. 6, in search of Clinton. 44663 Date Ave. Linda Stoltzfoos -- 18 at the time she disappeared -- was last seen on June 21. The arrest came when a woman called cops to inquire about the health of a relative. LANCASTER — A Pennsylvania man faces homicide charges after a human head was found in a freezer at his family's home and a dismembered body was found in a bed. A man was fatally shot Monday in the Lancaster area. Brown is one of the youngest people to be charged with homicide in Lancaster County history, although two other 14-year-olds have been charged with homicide here in the last two years. No further details have been released as the investigation into the. in Lancaster County, PA in June of 2022! We are currently taking bus tour and large group reservations. Lancaster Road Updated Post: January 20, 2021, On January 20, 2021, Rapheal Jefferson, a 33-year-old black male, was arrested for the murder of Kendrick Hampton that occurred at 3200 S Lancaster Road on January 5, 2021. Lancaster (KDKA) — A 32-year-old man from Lancaster has been arrested and charged with murder after police found a human head stored in a home freezer. Hey Guys! Today's video is on the case of Sophie Lancaster. An autopsy performed by the Lancaster County Coroner's Office determined Helen Miller, who suffered from cerebral palsy, had been stabbed several times. , 32, was arrested Wednesday in connection with the stabbing death and dismemberment of his father, Donald Meshey Sr. Investigators believe the victim ended a relationship with Matthew Vanzandt shortly. LANCASTER, N. In the last 5 years Lancaster has seen. Jan 27, 2021 · Updated: 5:00 PM EST February 4, 2021. Sophie was just 20 when died after being brutally attacked by a gang of teenage thugs in a Lancashire park. Donald Lawrence Meshey Jr. (MORE: DNA on gum, water bottle leads to DJ's arrest 26 years. 18 Murder Mysteries serving Lancaster, CA. , Sunday on the 44200 block of Beech Avenue, according to a report from Los Angeles County Sheriff's. LANCASTER, PA — The Lancaster Bureau of Police announced the arrest of Donald Meshey Jr. Two Lancaster County adults have been charged with criminal homicide related to the death of a four-month-old baby who drowned in a bathtub. LANCASTER, N. LANCASTER COUNTY, S. — Erie County District Attorney John Flynn announced that a Lancaster man has been charged with vehicular homicide and harassing the family of the deceased from a May 2019 incident. Help us do better. The main suspect in a weekend homicide is in custody after two days, Lancaster officials said Monday. Deputy District Attorney Michael Blake said Nicolas Olvera Cordoba, 63, Antonio Martínez, 51, and. The murder of Sophie Lancaster occurred in the United Kingdom in 2007. about 6 months ago. Offers Virtual Services. Top Posts Jun 21, 2021. In the last 5 years Lancaster has seen decreasing violent crime and decline of. Charles Wilbert Lancaster was shot in the 100 block of Ridge Road, SE. Lancaster County District Attorney Craig Stedman announces charges in the 1992 cold case killing of Christy Mirack during a news conference at the Lancaster County Courthouse in Lancaster, Pa. Field of Drafts™ Pre-Sale VIP Tickets Will Be Sold at The TRACE ADKINS: The Way I Wanna Go Tour on June 27. , Sunday on the 44200 block of Beech Avenue, according. Hey Guys! Today's video is on the case of Sophie Lancaster. Edition of Lancaster New Era. Donald Meshey Jr. Police say a Lancaster man is charged with homicide after a human head was found in a freezer at his apartment and he admitted to stabbing a "cadaver doll. (Before I start to discuss this murder, I would like to say that this murder affected me strongly, I live 33 minutes away from where the killings occurred. Get Alerts. In Lancaster you have a 1 in 37 chance of becoming a victim of crime. The 2019 crime rate in Lancaster, CA is 360 (City-Data. Six arrested after drug bust. Teen accused in York homicide is charged in deadly hit-and-run in Lancaster. - A Lancaster man is facing homicide and abuse of a corpse charges after a welfare check turned up a human head and body. With Neil Dudgeon, Gwilym Lee, Fiona Dolman, Manjinder Virk. Credit: Lancaster County Sheriff's Office. 2 per 100,000 population, a 0. SOUTHFIELD, Mich. (KLKN) — Lincoln police have identified the man killed in Sunday morning's homicide. Sep 07, 2021 · Man found shot and killed in Lancaster. SOPHIE Lancaster was murdered in August 2007 after she and boyfriend Robert Maltby were beaten and left for dead by a gang of drunken yobs. 4 hours ago · A Lancaster man was charged with homicide on Wednesday after he showed police a human head and admitted to stabbing a “cadaver doll” at his Cabbage Hill residence, according to Lancaster police. Lancaster offers a variety of murder mystery options from which to choose. When a wealthy landowner's body goes missing on the night of his death, a sinister web of secrets and lies is exposed in the village of Little Malton. Prosecutors say that in May of 2019, Allen Stirling, 49, was. South Middle School special education teacher Eleanor Mends passed away after battling COVID-19, according to school officials. Keyshawn Evanta Harris was arrested on a murder charge in the shooting death of Tony Evans Jr. SOPHIE Lancaster was murdered in August 2007 after she and boyfriend Robert Maltby were beaten and left for dead by a gang of drunken yobs. He told a court that he wanted the death penalty because he. , 32, also faces. LANCASTER COUNTY, S. Violent offenses tracked included rape, murder and non-negligent manslaughter, armed robbery, and aggravated assault, including assault with a deadly weapon. Police say a Lancaster man is charged with homicide after a human head was found in a freezer at his apartment and he admitted to stabbing a "cadaver doll. Authorities state that on August 11, 2021, at 8:51 am, officers from the Lancaster City Bureau of Police responded to 202 W. Leon Gilmore was taken into custody without incident and arrested for the murder of Jesse Gilmore. Local school districts debate mask mandates in classroom Video. Community content is available under CC-BY-SA unless otherwise noted. Yes, they absolutely have the killer's DNA in Erma Kaylor's brutal murder. 2013 Court Calendar (Jul - Dec) 2013 Court Calendar (Jan - Jun) 2012 Court Calendar. Lancaster crime rates are 9% higher than the national average. Navigating legal issues after the death of a loved one can be daunting and complex. Ryan Herbert, who murdered Sophie Lancaster in 2007, was ordered to serve a minimum 15. 2 days ago · A 65-year-old woman found dead inside her Lancaster County home last week died of strangulation, the coroner has ruled, according to the LNP newspaper. Two Lancaster County adults are charged with criminal homicide after a four-month-old baby under their care drowned in a bathtub. Warrants have been issued charging Clinton with attempted murder, failure to stop for blue lights, reckless driving and speeding. The Lancaster Police Department now has an online crime map called RAIDS Online that maps and analyzes crime data and alerts Lancaster citizens about crimes in their area. Brown is one of the youngest people to be charged with homicide in Lancaster County history, although two other 14-year-olds have been charged with homicide here in the last two years. Michael Thomas, 62, was killed. The victim and her boyfriend Robert Maltby were attacked by a number of teenage boys w. Remains were found near Dutchland Inc in Lancaster County on Wednesday In December last year Justo Smoker, 34, was charged with criminal homicide Dutchland Inc is the former workplace of Smoker. Lancaster was acquitted of murder after 5 hours of deliberation. Help us do better. A sign seeking information on the 1992 murder of Christy Mirack is seen in the Lancaster, Pa. Save this home. While Police have released the suspect’s name and photo, MyChesCo has chosen to not disclose the juvenile’s identity due to the suspect’s age. Lancaster man indicted in connection with fatal Richland Township shooting. Donald Meshey Jr. 20 helpful votes. was found dead in her East Lampeter Township home on Dec. 4 times lower than the U. com crime index), which is 1. , 32, is charged with criminal homicide, abuse of a corpse and tampering with evidence. Donald Meshey Jr. Lancaster Mar 27. Murder in Coweta County: Directed by Gary Nelson. LANCASTER (CBSLA. The shooting was at approximately 10:25 p. We will open individual ticket sales in February for our Summer Season. Hollywood sexual antics led to the murder of Natalie Wood. Murder of her husband, Frederick. (The US average is 35. Yes, they absolutely have the killer's DNA in Erma Kaylor's brutal murder. , a 17-year-old standout senior wide receiver at Lancaster High School in Texas. Three other Pennsylvania counties ranked in the top five in the nation, and overall, prosecutors in Pennsylvania filed the charge more than in any other state. A man and woman from Lancaster County have been charged with homicide in connection with the death of a 4-month-old in May. LANCASTER — Los Angeles County Sheriff's Department Homicide detectives continued their investigation Monday morning into the circumstances surrounding the shooting death of man near downtown Lancaster. The Lancaster Police Department and BAIR Analytics Inc. The Lancaster Police Department now has an online crime map called RAIDS Online that maps and analyzes crime data and alerts Lancaster citizens about crimes in their area. She formed the Sophie Lancaster Foundation to create respect for subcultures and hopes this episode will urge victims of hate crime to come forward. in Lancaster County earlier this month. The shooting was reported about 10:10 a. The Lancaster PA murder/homicide rate for 2018 was 3. Murder In Lancaster County The history and background of at least two local murders in Lancaster County, PA. Officers found Ruth A. Declan Lancaster had been charged with the murder of Patryk Mortimer but admitted manslaughter when he appeared at Newcastle Crown Court. A Fairfield County jury has found a woman not guilty of vehicular homicide in the death of a young father. Ricardo Lancaster's Family Begs for Mercy for Grant Johnson at Murder Sentencing Posted Feb. 44 miles from Lancaster. — Officials say a second middle school teacher has died from COVID-19 complications in Lancaster County. , 32, was arrested Wednesday in connection with the stabbing death and dismemberment of his father, Donald Meshey Sr. LANCASTER, Pa. by Megan Arellano Before he was sentenced Friday to 49 years in prison, Grant Johnson spoke at length about how prosecutors vilified him. A man was fatally shot Monday in the Lancaster area. Sep 08, 2021 · Beloit homicide victim likely killed 2 days before body was found, police chief says Obituaries Wednesday September 8, 2021 Grant County Man Tased After Resisting Arrest Shullsburg Woman Arrested For Drug Possession Milk Truck Overturns in Northern Grant County Republicans, elections experts say Wisconsin probe is flawed Vehicle Rear-ends Amish. 5, after being shot near 4323 Floral Drive in East Los Angeles, according to Los Angeles County Medical Examiner-Coroner's records. LANCASTER COUNTY, S. 35 per 100,000 population, a 60. Save this home. 2 days ago · A 65-year-old woman found dead inside her Lancaster County home last week died of strangulation, the coroner has ruled, according to the LNP newspaper. According to authorities, the caller stated that Meshey informed her that there was a. Raymond Charles Rowe, 49, was arrested in. The 2019 Lancaster crime rate fell by 97% compared to 2018. "I'm sorry, sir, to the family," said Raymond Charles Rowe, who performed under the name DJ Freez, as he. When they arrived, they found two male Hispanics in their 30s, suffering from gunshot wounds to their upper torsos. South Middle School special education teacher Eleanor Mends passed away after battling COVID-19, according to school officials. , the Los Angeles Times' resource for boundaries, demographics, schools and news within the city. 2 days ago · A 65-year-old woman found dead inside her Lancaster County home last week died of strangulation, the coroner has ruled, according to the LNP newspaper. by Megan Arellano Before he was sentenced Friday to 49 years in prison, Grant Johnson spoke at length about how prosecutors vilified him. According to. Navigating legal issues after the death of a loved one can be daunting and complex. I also attended the college she wanted to…. Murdered for Being Different: The harrowing true story of Sophie Lancaster's murder. com crime index), which is 1. (KABC) -- A father has been arrested on suspicion of murder after two of his children, a 12-year-old boy and 13-year-old girl, were found decapitated at a Lancaster home. — Deputies said a suspect wanted for shooting and killing a man in. Ricardo Lancaster's Family Begs for Mercy for Grant Johnson at Murder Sentencing Posted Feb. Lincoln police identify suspect in homicide investigation. LANCASTER, PA — The Lancaster City Bureau of Police has announced the arrest of a 14-year old juvenile in connection to the murder of Rolando Rivera, on August 27, 2021. Margaret Wishart. Local school districts debate mask mandates in classroom Video. Sophie Lancaster's mum, Sylvia, The murder charges against the other three - two 15-year-olds and a 17-year-old who were kept anonymous - were dropped. Sep 07, 2021 · Man found shot and killed in Lancaster. Sharpo! Mystery & Magic - Top Rated. Leon Gilmore was taken into custody without incident and arrested for the murder of Jesse Gilmore. Lancaster offers a variety of murder mystery options from which to choose. Local Lancaster Newspapers. Sep 07, 2021 · Two Lancaster County adults are charged with criminal homicide after a four-month-old baby under their care drowned in a bathtub. Jimmy Mummau before Magisterial. Habeas Corpus: Directed by Alex Pillai. Three Dead In Overnight Lancaster Murder-Suicide. The body of Nora. However, he was only ever charged for the triple homicide in Lancaster. Lancaster police say a man was arrested after he killed his father and dismembered his body. LANCASTER — Deputies with the Lancaster Sheriff's Station responded to a call regarding a shooting at 10:10 a. Donald Meshey Jr. A 65-year-old woman found dead inside her Lancaster County home last week died of strangulation, the coroner has ruled, according to the LNP newspaper. Chambersburg Elks Lodge looking to raise $30,000 to reopen Video. September 7, 2021. Prosecutors say that in May of 2019, Allen Stirling, 49, was. Murder in Coweta County: Directed by Gary Nelson. Lancaster police have now officially charged and released the names of the one adult and the three teens in the case. for Women: 446787 / 291355 Robbery(1) ZAAYER, FRANCES : KY Corr. 3 times greater than the U. Lancaster (KDKA) — A 32-year-old man from Lancaster has been arrested and charged with murder after police found a human head stored in a home freezer. LANCASTER — Los Angeles County Sheriff’s Department Homicide detectives continued their investigation Monday morning into the circumstances surrounding the shooting death of man near downtown Lancaster. (Before I start to discuss this murder, I would like to say that this murder affected me strongly, I live 33 minutes away from where the killings occurred. Sunday, March 8, 2009. An autopsy performed by the Lancaster County Coroner's Office determined Helen Miller, who suffered from cerebral palsy, had been stabbed several times. , 67, died of multiple stab wounds to his body. (The US average is 22. In the last 5 years Lancaster has seen. LANCASTER — When Hermela Gebremeskel had brought her two children to the United States from Eritrea, she hoped they. Leon Gilmore is currently being held in the Fairfield County. , on the 44000 block of 15th Street West in Lancaster, according to investigators. 1 day ago · LANCASTER, S. Rex Parris told the Los Angeles Times that both victims were decapitated, calling the incident "pretty brutal. The body of Nora. Community content is available under CC-BY-SA unless otherwise noted. Lancaster Mayor R. DJ who killed and raped teacher in 1992 caught after sister uploads DNA to genealogy site. Mother arrested in 2007 Lancaster homicide, accused of killing newborn and putting body in Dumpster. Sophie Lancaster and her boyfriend Robert Maltby were violently assaulted by a group of young people after being set upon in a park in an unprovoked attack in 2007. He told a court that he wanted the death penalty because he. The shooting was at approximately 10:25 p. 36% decline from 2017. David Meadows and Amy Manning are the parents of the victim. Police say, David Meadows, 27, of Ronks, was arrested Friday morning in West Earl. According to. (FOX 46 CHARLOTTE) - A man accused of shooting and killing a 46-year-old man near Kershaw on August 1 turned himself in to authorities Wednesday, according to the Lancaster County Sheriff's Office. Links We Mentioned. Authorities state that when officers arrived at the scene, they discovered a male victim lying in the street. LANCASTER, Pa. on the 44100 block of Sierra Highway, Lancaster, deputies responded to the location regarding an unresponsive male adult. LANCASTER — Los Angeles County Sheriff's Department Homicide detectives continued their investigation Monday morning into the circumstances surrounding the shooting death of man near downtown Lancaster. 2017 Court Calendar. There were 6 in the entire month of July. However, he was only ever charged for the triple homicide in Lancaster. Sep 07, 2021 · Two Lancaster County adults are charged with criminal homicide after a four-month-old baby under their care drowned in a bathtub. A person of interest has been detained and will be interviewed by homicide detectives, according to the Sheriff's Department. LANCASTER — Los Angeles County Sheriff’s Department Homicide detectives continued their investigation Monday morning into the circumstances surrounding the shooting death of man near downtown Lancaster. The Lancaster Police Department is searching for 27-year-old Quinterius Lamont Clinton, of 1627 Kaywood Drive. The shooting was reported around 10:10 a. , 32, is charged with criminal homicide, abuse of a corpse and. The victim and her boyfriend Robert Maltby were attacked by a number of teenage boys w. Lancaster Sheriff's Office 1520 Pageland Hwy. Re: Murder mystery train. SOUTHFIELD, Mich. If you have any information on this unsolved case you are asked to contact the Lancaster Police Department (716) 683-2800 or the Erie County District Attorney's Office (716) 858-2400. A little over 30 years ago, a Northern Neck fisherman named Emerson Stevens went to prison for the brutal slaying of a homecoming queen and mother of two. and Robert E. South Middle School special education teacher Eleanor Mends passed away after battling COVID-19, according to school officials. Together we can ease the pain and prevent further victimization. The man, who was not immediately identified, died at the scene, the sheriff’s department reported. - A Lancaster man is facing homicide and abuse of a corpse charges after a welfare check turned up a human head and body. While a number of different hypotheses are set forth, the actual reason for the murder is unclear. 5, after being shot near 4323 Floral Drive in East Los Angeles, according to Los Angeles County Medical Examiner-Coroner's records. Los Angeles County Sheriff's Homicide investigators are continuing to investigate the circumstances surrounding the shooting death of a male White adult that occurred on the 44200 block of Beech Ave. deputies were dispatched to 218 Railroad Avenue just north of the Town of Kershaw off North Matson Street. On this site, you'll find out what to do, where to stay, places. A homicide investigation has been launched after a woman was discovered dead in her New Holland home on Wednesday. 2018 Court Calendar. LANCASTER, N. These murders are informally known as the Bodies Under the Bridge and. So far we've gathered pictures of 1,638 victims, about 9% of those killed. A statement from Lancaster County School. in Lancaster County, PA in June of 2022! We are currently taking bus tour and large group reservations. (FOX 46 CHARLOTTE) - A man accused of shooting and killing a 46-year-old man near Kershaw on August 1 turned himself in to authorities Wednesday, according to the Lancaster County Sheriff's Office. It was higher than in 89. 01 acres lot. 66 (17) Los Angeles, CA. Crime Map for Lancaster, PA. — Officials say a second middle school teacher has died from COVID-19 complications in Lancaster County. The Lancaster TX murder/homicide rate for 2016 was 10. Lancaster police have now officially charged and released the names of the one adult and the three teens in the case. Saturday, February 27, 2021 at 4:00 PM UNK - 6:00 PM UNK. Two Lancaster County adults have been charged with criminal homicide related to the death of a four-month-old baby who drowned in a bathtub. Lancaster Mayor R. , Jean Hargadon Wehner, a 16-year-old junior at the all-girls Catholic school, followed the priest to the parking lot and climbed into the passenger seat of his light blue. A man has been ordered to stand trial on a homicide charge in the disappearance of a young Amish woman in Pennsylvania last summer. The 2019 crime rate in Lancaster, CA is 360 (City-Data. 1 Synopsis 2 Plot 3 Cast 4 Galleries 4. "That was … a day," he. A homicide investigation has been launched after a woman was discovered dead in her New Holland home on Wednesday. Sunday morning. Richard Gehman's A MURDER IN PARADISE is a true crime account of the 1950 murder of Franklin Marshall College clerical worker Marian Baker by student Edward Gibbs in Lancaster, PA. Deputies were sent to 218 Railroad avenue just before 5AM that day and that's where they found Kenneth Morehead Jr. A man was arrested and charged with murder after his two children were found dead in a Lancaster home, Friday. 87% decline from 2015. There have been 56,380 confirmed cases in the county. — A man and woman from Lancaster County have been arrested and charged with homicide in connection to the drowning death of a four-month-old baby at a hotel on Lincoln Highway East. Prince William County police investigators believe a 44-year-old woman was 'justified' when she shot a man to death as he approached wearing a mask and armed with a handgun. (FOX 46 CHARLOTTE) - A man accused of shooting and killing a 46-year-old man near Kershaw on August 1 turned himself in to authorities Wednesday, according to the Lancaster County Sheriff's Office. in Lancaster County earlier this month. A 65-year-old woman found dead inside her Lancaster County home last week died of strangulation, the coroner has ruled, according to the LNP newspaper. Murder of her husband, Frederick. For Lancaster, we found that the violent crime rate is one of the highest in the nation, across communities of all sizes (both large and small). He told a court that he wanted the death penalty because he. The Lancaster Police Department and BAIR Analytics Inc. Lancaster, Pa. According to Fairfield County Sheriff Alex Lape, deputies were. Lancaster, S. LANCASTER, Ohio - Lancaster police are investigating the deaths of an elderly couple this morning as a murder-suicide. Lancaster police said Steffan Vadoria Tidwell turned himself into city detectives at the. The number of homicides stood at 7. The coroner determined the manner of death for Nora Sanchez as homicide, Adams said. Remains were found near Dutchland Inc in Lancaster County on Wednesday In December last year Justo Smoker, 34, was charged with criminal homicide Dutchland Inc is the former workplace of Smoker. The victim's cellmate, a San Diego man, is a suspect. Jobs Terms. Lancaster County deputies are now investigating the death of a woman as a homicide, officials said. , 67, by Lancaster police. Justo Smoker, 35, awaits trial on homicide charges after allegedly kidnapping Linda Stoltzfoos 10 months ago. It was higher than in 4. Police: Lancaster man charged with homicide after human head found in freezer. Now we are expanding that goal to include a photograph for every victim. 2011 Court Calendar. 4) NOTE: Click on the links below to see charts for each crime category. Prince William County police investigators believe a 44-year-old woman was 'justified' when she shot a man to death as he approached wearing a mask and armed with a handgun. The Lancaster Police Department now has an online crime map called RAIDS Online that maps and analyzes crime data and alerts Lancaster citizens about crimes in their area. 476 Hubbard Dr, Lancaster, SC 29720. LANCASTER, Pa. , 32, is charged with criminal homicide, abuse of a corpse and tampering with evidence. Mollie Gallagher, who plays Nina Lucas in Coronation Street, has tonight won a National Television Award for a storyline which mirrored the murder of Sophie Lancaster. 12/30/20 Update: Preliminary hearing for murder charge was postponed. Lancaster police said Steffan Vadoria Tidwell turned himself into city detectives at the. A man has been ordered to stand trial on a homicide charge in the disappearance of a young Amish woman in Pennsylvania last summer. (CN2 NEWS) – The Lancaster County Sheriff’s Office is investigating a homicide in Kershaw after officials say a man died after being shot multiple times. Four men convicted of first-degree murder with special circumstance allegations were sentenced today in connection with killings at a doctor's ranch in Lancaster, the Los Angeles County District Attorney's Office announced. In the last 5 years Lancaster has seen. LANCASTER — When Hermela Gebremeskel had brought her two children to the United States from Eritrea, she hoped they. See live updates from Lancaster where a homicide is under investigation. Phillip Cornelius Sullivan, II struck a horse drawn buggy (su…. Lancaster Sheriff's Office 1520 Pageland Hwy. LANCASTER, S. The Lancaster County Sheriff's Office is investigating a homicide that occurred near Kershaw early Sunday morning, August 1, 2021. 16/06/1827. No further details have been released as the investigation into the. Get the details. Prosecutors say that in May of 2019, Allen Stirling, 49, was. (The US average is 22. -- An accused killer from Monroe County is facing homicide charges in Lancaster County. A report of a head in a freezer led Lancaster investigators to a home on Wednesday morning, where they found. Second man arrested, charged with murder in Lancaster double homicide. , on the 44000 block of 15th Street West in Lancaster, according to investigators. 44663 Date Ave. Sep 07, 2021 · Man found shot and killed in Lancaster. 45, with multiple gunshot wounds to his upper body. SOPHIE Lancaster was murdered in August 2007 after she and boyfriend Robert Maltby were beaten and left for dead by a gang of drunken yobs. , the Los Angeles Times' resource for boundaries, demographics, schools and news within the city. LANCASTER, SC (WBTV) - A second person has been charged in connection to a deadly June shooting at the Palmetto Place Apartment complex in Lancaster. If you have a photo of a homicide victim to share, email it to [email protected] Murder of her bastard child. Prince William County police say homicide was justifiable. LANCASTER (CBSLA) - The father of a 12-year-boy and 13-year-old girl found dead at a Lancaster home has been arrested on suspicion of killing. The Lancaster TX murder/homicide rate for 2016 was 10. Lancaster police say a man was arrested after he killed his father and dismembered his body. Since then, he has been held in Lancaster County Prison. in Lancaster County earlier this month.

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